Neurofeedback-based Visual Restoration Therapy for Chronic Visual Field Defects

What this Trial Is About

Visual field defects often occur after acquired brain injuries and can make daily activities like reading, driving, and moving around safely difficult. This research aims to evaluate whether neurofeedback therapy can improve vision in people with chronic visual field defects, particularly those who are at least 50 years old. The study builds on previous findings that neurofeedback can enhance brain communication and improve mobility after stroke, focusing here on visual ability such as visual field expansion and contrast sensitivity. Participants will undergo neurofeedback training using high-density EEG and advanced brain signal analysis to provide real-time audio feedback. During the active phase, patients receive feedback linked to brain activity in visual areas to help improve brain connectivity. The control phase uses synthetic feedback that mimics real feedback but is not linked to actual brain activity. Each training session lasts about 40 minutes with breaks and is followed by visual stimulation of the affected visual field designed to promote steady-state visual evoked potentials. Throughout the study, researchers will measure changes in the visual field at 3 weeks and 7 weeks, along with changes in alpha-band brain connectivity, the impact of visual impairment on daily life via questionnaires, and reading speed. The study uses a randomized, double-blind design and includes monitoring to assess how neurofeedback affects vision and brain function over the treatment period. Participation is expected to last at least 7 weeks from enrollment through follow-up.

Neurofeedback-based Visual Restoration Therapy