Actively Recruiting

Phase Not Applicable
Age: 7Years - 80Years
All Genders
ID04424979

Visual Field Expansion Through Innovative Multi-Periscopic Prism Design

Led by Massachusetts Eye and Ear Infirmary · Updated on 2025-09-23

20

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

Sponsors

M

Massachusetts Eye and Ear Infirmary

Lead Sponsor

N

National Eye Institute (NEI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are developing and testing different designs of high-power prisms to help people who have lost part of their vision field. These prisms aim to expand their field of vision to improve obstacle detection while walking. The study focuses on finding the best prism designs and fitting methods for future clinical use in patients with conditions like homonymous hemianopia, tunnel vision, and other visual field defects. Participants will receive custom-fitted high-power prisms incorporated into spectacle lenses. Each individual will have multiple visits, usually four, to the research institute for fitting and testing of their prism glasses. The study does not include placebo or comparison groups, and the focus is on evaluating different prism configurations tailored to each participant. During the study, participants will undergo several assessments over about four months to measure the expansion of their field of view and their ability to detect pedestrians. These visits will last between 2 to 4 hours, and participants must be able to walk short distances independently. Researchers will monitor how well the prisms work and how participants adjust to wearing them, collecting data that will guide future prism device development.

CONDITIONS

Brief Title

Feasibility Tests for Various Prism Configurations for Visual Field Loss

Who Can Participate

Age: 7Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Visual field loss, either peripheral field loss or hemianopic field loss
  • Visual acuity of at least 20/50 in the better eye
  • In sufficiently good health to be able to complete sessions lasting 2-4 hours
  • Able to independently walk short distances
  • Able to give voluntary, informed consent
  • Able to speak English
Not Eligible

You will not qualify if you...

  • Any physical or mental impairments, including cognitive dysfunction, balance problems or other deficits that could impair the ability to walk or use the prism spectacles
  • A history of seizures in the last 6 months
  • Hemispatial neglect (subjects with hemianopic field loss only)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Up to 4 months

Participants receive custom-fitted spectacles with various configurations of high power prisms designed to shift images from blind areas into their remaining field of vision.

Multiple visits for fitting and assessments

Trial Site Locations

Total: 1 location

1

Schepens Eye Research Institute

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

A

Alex Bowers

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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Frequently Asked Questions

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Published Research Related To This Trial

Pilot study of a pedestrian collision detection test for a multisite trial of field expansion devices for hemianopia.

Alex R Bowers, Sailaja Manda, Sandhya Shekar...

https://pubmed.ncbi.nlm.nih.gov/38990239