Actively Recruiting
Neurophysiologic Biomarkers for Cognitive Rehabilitation
Led by VA Office of Research and Development · Updated on 2025-10-09
80
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cognitive symptoms of schizophrenia interfere with daily life-from managing self-care, to more complex tasks like taking medications and living independently. Unfortunately, these cognitive symptoms are not corrected by 'standard of care' treatments (antipsychotic medications), although some schizophrenia patients may experience modest clinical and cognitive benefits from cognitive remediation. To enhance the clinical impact of cognitive remediation and other rehabilitative interventions for Veterans living with chronic psychosis, this study will develop novel brain-based tools to help identify those Veterans who are most likely to benefit from pro-cognitive therapies. These studies may advance predictive algorithms that improve functional outcomes and life quality in Veterans with schizophrenia.
CONDITIONS
Official Title
Neurophysiologic Biomarkers for Cognitive Rehabilitation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have a DSM-5 diagnosis of a chronic psychotic disorder, such as schizophrenia, schizoaffective disorder, or delusional disorder; or are in good general mental and physical health with no active mental health condition
- Fluent in spoken and written English
- No impairment in hearing or vision
You will not qualify if you...
- Active substance use other than cannabis within the last 30 days as determined by self-report or urine toxicology
- History of significant medical or neurological illness or intellectual disability
- Inability to comprehend or provide informed consent
- Healthy comparison subjects with any past or present diagnosis of schizophrenia, schizoaffective disorder, or other chronic psychotic disorder
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VA San Diego Healthcare System, San Diego, CA
San Diego, California, United States, 92161-0002
Actively Recruiting
Research Team
J
Juan Molina, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here