The prevalence of schizophrenia and other psychotic disorders among homeless people: a systematic review and meta-analysis.
Getinet Ayano, Getachew Tesfaw, Shegaye Shumet
https://pubmed.ncbi.nlm.nih.gov/31775786/Actively Recruiting
Led by VA Office of Research and Development · Updated on 2025-11-10
50
Participants Needed
1
Research Sites
13 weeks
Total Duration
This research aims to evaluate a brief behavioral intervention combining Motivational Interviewing MI and Cognitive Behavioral Therapy CBT to improve community integration in Veterans with serious mental illness SMI who have experienced homelessness. The study addresses challenges faced by Veterans transitioning from temporary to permanent housing, including maintaining mental healthcare and daily functioning. It compares this intervention with a time- and format-matched control that includes remote mindfulness training. Participants will be randomized into two groups one receiving the MI-CBTech intervention and the other receiving supportive therapy with mindfulness training. Both treatments last 8 weeks and include three initial in-person sessions followed by six weeks of mobile phone application use. Remote check-ins by phone occur during weeks 2, 4, and 6 to support application use and address any issues. The interventions leverage participants own smartphones, with devices provided if needed. Veterans will undergo a baseline in-person assessment including interviews and cognitive tests before randomization. Outcome measures include completion rates of baseline, end of treatment, and follow-up assessments, as well as treatment adherence and satisfaction ratings. Follow-up assessments occur 16 weeks after baseline and can be done in person or remotely. Total assessment time is approximately 4 hours at baseline and 2 hours for subsequent visits. This study will help guide future larger trials to improve care during critical housing transitions.
CONDITIONS
MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI
A
Amy M Jimenez, PhD
M
Michael F Green, PhD
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VA Office of Research and Development
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | MI-CBTech Mobile App plus In-Person Motivational Interviewing and CBT | Supportive Therapy plus Mindfulness-Based Mobile App |
|---|---|---|
| What it is | A behavioral intervention combining three in-person motivational interviewing sessions with cognitive behavioral therapy, followed by six weeks of a mobile app delivering CBT content, skills training, tailored worksheets, and crisis resources. | Three in-person supportive therapy sessions focusing on empathic listening and mindfulness introduction, plus six weeks of a mindfulness-based training app with audio exercises, information, goal setting, and crisis resource access. |
| Role in study | Investigational intervention combining MI and CBT, studied for impact on community integration and adherence. | Active comparator providing supportive therapy and mindfulness-based coping, serving as control arm. |
| Primary use or intended benefit | To support community integration and address unhelpful thinking patterns in homeless-experienced veterans with serious mental illness, using digital CBT and motivational interviewing strategies. | To enhance coping, stress management, and self-awareness through supportive therapy and structured mindfulness exercises. |
| How it is given or performed | Three in-person MI-CBT sessions followed by six weeks of individualized CBT content, exercises, and resources delivered via a mobile phone application. | Three supportive therapy sessions with mindfulness introduction, then six weeks of mobile app-based mindfulness exercises, information, tracking, and crisis support. |
| Evidence status | Digital and mobile CBT and motivational interviewing combinations are under active clinical study; meta-analyses suggest potential to improve psychiatric symptoms and treatment adherence, but evidence in homeless-experienced veterans remains early-stage. | Mindfulness-based and supportive digital interventions are supported by evidence as feasible and acceptable in serious mental illness, but direct comparative data versus CBT-based mobile approaches are limited. |
| Important limitations | Effectiveness in homeless-experienced veterans with serious mental illness is not yet established. Engagement may depend on participants’ ability to use and regularly access mobile technology. | Digital mindfulness approaches show feasibility, but direct evidence for improvement in community integration or specific psychiatric outcomes in this population is limited. Mobile intervention success may vary by individual technology access and engagement. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete baseline assessments including symptom ratings, community functioning interviews, and cognitive ability tests before randomization.
1 baseline visit (in-person)
Duration - 8 weeks
Participants receive an 8-week intervention consisting of three in-person sessions during the first 2 weeks followed by 6 weeks of mobile application use. Phone check-ins occur during weeks 2, 4, and 6 to support application use and troubleshoot any issues.
3 in-person sessions and 3 phone check-ins
Duration - 1 day
Participants complete symptom ratings and community functioning assessments to evaluate treatment effects. Assessments may be completed in-person or remotely by phone or videoconference.
1 visit (in-person or remote)
Duration - 1 day
Participants complete final symptom ratings, community functioning assessments, and an exit interview approximately 16 weeks after baseline to evaluate longer-term outcomes.
1 visit (in-person or remote)
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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Lead Sponsor