Actively Recruiting

Age: 18Years +
All Genders
NCT07125352

Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Led by Ain Shams University · Updated on 2025-08-15

190

Participants Needed

1

Research Sites

40 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic obstructive pulmonary disease (COPD) stands as one of the leading causes of mortality worldwide. Acute exacerbations of COPD (AECOPD) lead to rapid respiratory function decline and worsened disease status. Despite recent studies, the ability of the neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in patients with COPD remains controversial. It remains controversial whether NLR can predict clinical outcomes in hospitalized patients with AECOPD. Therefore, this study was conducted to investigate the predictive value of NLR for severity, adverse outcomes in hospitalized patients with AECOPD, and predicting treatment response in patients with AECOPD

CONDITIONS

Official Title

Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 and above
  • Patients admitted to the Chest department, Ain-Shams University Hospitals
  • Diagnosed with acute exacerbation of COPD (AECOPD) based on the Global Initiative for Chronic Obstructive Lung Disease 2024 criteria
Not Eligible

You will not qualify if you...

  • Patients who refused treatment
  • COPD patients with malignancy
  • COPD patients with hematological disorders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ain Shams University

Cairo, Abbasyea, Egypt, 02

Actively Recruiting

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Research Team

H

Hieba G Ezzelregal, MD

CONTACT

M

mona A alhady, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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