Preoperative Neutrophil-to-Lymphocyte Ratio as a Predictor of Post-Dural Puncture Headache Following Cesarean Section Under Spinal Anesthesia

What this Trial Is About

Researchers are investigating whether systemic inflammatory markers, especially the neutrophil-to-lymphocyte ratio (NLR) from preoperative blood counts, can predict the development of post-dural puncture headache (PDPH) in women undergoing cesarean section with spinal anesthesia. This observational study focuses on comparing patients who develop PDPH to those who do not after this procedure. The trial is led by Istinye University and aims to improve understanding of PDPH risk factors in obstetric patients. The study observes preoperative inflammatory markers including NLR, platelet-to-lymphocyte ratio (PLR), and systemic inflammatory response index (SIRI) without administering any additional treatment or intervention. Participants are grouped based on the presence or absence of PDPH following spinal anesthesia during cesarean section. No experimental treatments are given, as the study relies on analyzing existing blood count data and medical records. Participants will be monitored for the incidence of post-dural puncture headache within 10 days after surgery. Researchers will review preoperative blood tests and postoperative medical records to assess PDPH development. The study involves collecting and analyzing data from patient records to evaluate whether inflammatory markers can serve as predictors. The total participation duration varies depending on the follow-up period after the cesarean section.

Neutrophil to Lymphocyte Ratio and Postdural Headache