Norris ORIEN Total Cancer Care Protocol: A Lifetime Partnership With Patients

What this Trial Is About

Researchers are collecting biological samples and clinical information from patients who have cancer or are at risk for cancer to create a large repository. This study aims to combine genetic data from these samples with clinical information to better understand why some cancers respond to treatment and to help develop more personalized medicine. It is a long-term observational study following patients through their lifetime with active or passive follow-up. Participants provide blood samples up to four times a year during regular care visits. Extra tissue is collected during standard surgery, and additional tumor samples may be taken during planned biopsies. Bone marrow may be sampled up to four times a year with careful needle repositioning. Other biological samples like saliva, sputum, urine, feces, hair, and skin swabs are also collected. Alongside sample collection, participants complete surveys about demographics, medical and family history, cancer risk factors, quality of life, and quality of care. During the study, participants are followed periodically even after initial data collection. Researchers review medical charts and assess quality of life through questionnaires. The primary outcome is the number of biospecimens collected and linked to clinical data over up to 21 years. This helps build a resource for future studies matching patients to new research opportunities.

Norris ORIEN Total Cancer Care