Actively Recruiting
Novel Biomarkers and Postoperative Kidney Injury in Radical Nephrectomy
Led by Peking University First Hospital · Updated on 2025-09-08
60
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The incidence of acute kidney injury (AKI) after radical nephrectomy exceeds 40%. Currently, the KDIGO criteria are the recognized diagnostic standard for AKI. These criteria primarily use serum creatinine and urine output as key indicators, but both parameters have certain limitations, such as delayed response, insensitivity, and inaccuracy. This study aims to simultaneously monitor perioperative novel renal damaging, stressful, and functional biomarkers in patients undergoing radical nephrectomy, and to investigate their predictive value for AKI and postoperative 1-year chronic kidney disease (CKD).
CONDITIONS
Official Title
Novel Biomarkers and Postoperative Kidney Injury in Radical Nephrectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Scheduled to undergo unilateral radical nephrectomy
You will not qualify if you...
- Having only one kidney
- Diagnosis of chronic kidney disease stages G4 or G5 (GFR <30 mL/min/1.73m2) before surgery
- Tumor invasion of the vena cava that requires thrombectomy
- Any other conditions judged unsuitable by the investigator for study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital
Beijing, Beijing Municipality, China, 100034
Actively Recruiting
Research Team
Q
Qiongfang Wu, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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