Actively Recruiting
Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States
Led by University of Southern California · Updated on 2025-10-01
90
Participants Needed
2
Research Sites
226 weeks
Total Duration
On this page
Sponsors
U
University of Southern California
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this program, the investigators will develop novel multimodal neural-behavioral-physiological monitoring tools (software and hardware), and machine learning models for mental states within social processes and beyond. The tools consist of a multimodal skin-like wearable sensor for physiological and biochemical sensing; a conversational virtual human platform to evoke naturalistic social processes; audiovisual affect recognition software; synchronization tools; and machine learning methods to model the multimodal data. The investigators will demonstrate the tools in healthy subjects without neural recordings and in patients with drug-resistant epilepsy who already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for standard monitoring to localize seizures, which is unrelated to our study.
CONDITIONS
Official Title
Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older able and willing to give informed consent
- Patients with drug-resistant epilepsy who already have intracranial EEG electrodes implanted for clinical seizure localization
- Patients aged 18 years or older with implanted electrodes willing to participate and able to follow research instructions
- Healthy adults over 18 years able and willing to participate
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Rancho Los Amigos National Rehabilitation Center
Downey, California, United States, 90242
Actively Recruiting
2
University of Southern California
Los Angeles, California, United States, 90007
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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