Monitoring Blood Pressure at Home and with Ambulatory Devices in Children and Adolescents with Elevated Blood Pressure

What this Trial Is About

Researchers are conducting a prospective observational study involving pediatric patients aged 6 to under 19 years who have been referred for elevated blood pressure. The study aims to evaluate whether home blood pressure monitoring HBP can identify blood pressure phenotypes, such as normotensive, hypertensive, masked hypertension, and white coat hypertension, as accurately as ambulatory blood pressure monitoring ABPM in children and adolescents. This research is sponsored by the Childrens Hospital Medical Center, Cincinnati. Participants will have an initial clinic visit where consent is obtained, and a detailed medical history is collected. They will undergo an echocardiogram ECHO and non-invasive vascular measurements including central blood pressure, augmentation index, and pulse wave velocity. An ABPM device will be placed, and participants will be trained to use an FDA-approved home blood pressure monitor, which they will take home. After one day, the ABPM device is returned by mail, and participants continue to measure their blood pressure at home for 20 days. Throughout the study, researchers will collect blood pressure data from both ABPM and HBP devices and assess blood pressure phenotype 6 to 12 months after enrollment. They will also examine the correlation between home blood pressure readings and signs of end organ damage within the same timeframe. Participants clinical stability and medication use will be monitored, with no treatment interventions involved. The total study duration extends through early 2028, allowing for comprehensive follow-up and analysis.

Office, Home, and Ambulatory Blood Pressure