Study of Full Body Standing X-rays in Healthy Adults Ages 21 to 85 Using EOS Imaging to Understand Normal Skeletal Changes Over Time

What this Trial Is About

Researchers are studying the skeletal structure and how it changes over time to understand normal bone changes as people age. This study evaluates full-body skeletal alignment in healthy adults from age 21 to 85 using a new low-dose x-ray system called EOS. The goal is to create an open access database of full-body images and spine parameters to provide reference data for spine surgeons and researchers, helping guide clinical decisions and further studies on spinal and other conditions. Participants will undergo one EOS scan, which captures full-body radiographs in standing positions from front and side views. Measurements taken include spinal alignment, pelvic angles, and joint flexion and extension at hips, knees, and ankles. The study will include 25 male and 25 female volunteers per decade of age, all without spine deformities or severe chronic diseases. This single imaging visit takes about 20 minutes. During the study, participants will have their skeletal parameters measured through this one-time imaging procedure. Researchers will analyze various alignment and posture measurements such as coronal plumb-line, sagittal vertebral axis, cervical lordosis, thoracic kyphosis, lumbar lordosis, pelvic tilt, and more. The study also monitors for safety by excluding participants with conditions that could affect bone structure or x-ray suitability. Participation involves only one visit for the imaging session, with no ongoing treatment or follow-up required.

Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers