Actively Recruiting

Phase Not Applicable
Age: 21Years - 85Years
All Genders
Healthy Volunteers
ID03076658

Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers

Led by University of Colorado, Denver · Updated on 2023-09-28

60

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the skeletal structure and how it changes over time to understand normal bone changes as people age. This study evaluates full-body skeletal alignment in healthy adults from age 21 to 85 using a new low-dose x-ray system called EOS. The goal is to create an open access database of full-body images and spine parameters to provide reference data for spine surgeons and researchers, helping guide clinical decisions and further studies on spinal and other conditions. Participants will undergo one EOS scan, which captures full-body radiographs in standing positions from front and side views. Measurements taken include spinal alignment, pelvic angles, and joint flexion and extension at hips, knees, and ankles. The study will include 25 male and 25 female volunteers per decade of age, all without spine deformities or severe chronic diseases. This single imaging visit takes about 20 minutes. During the study, participants will have their skeletal parameters measured through this one-time imaging procedure. Researchers will analyze various alignment and posture measurements such as coronal plumb-line, sagittal vertebral axis, cervical lordosis, thoracic kyphosis, lumbar lordosis, pelvic tilt, and more. The study also monitors for safety by excluding participants with conditions that could affect bone structure or x-ray suitability. Participation involves only one visit for the imaging session, with no ongoing treatment or follow-up required.

CONDITIONS

Brief Title

Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers

Who Can Participate

Age: 21Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females age 21 to 85
  • No history of spine surgery
Not Eligible

You will not qualify if you...

  • History of spine or neural axis surgery
  • History of cancer with or without metastatic disease
  • Connective tissue, rheumatologic, or neurologic disorders
  • History of knee replacement surgery
  • Severe osteoarthritis of hips, knees, or ankles
  • Spondylitis
  • Compression fractures or trauma of the spine
  • Previous trauma or fractures of pelvis or lower extremities requiring surgery
  • Pregnant women
  • Body mass index (BMI) greater than 37
  • Oswestry Disability Index score greater than 25

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo full-body radiographs using the EOS imaging system to obtain detailed spinal and pelvic alignment measurements.

1 visit (in-person, approximately 20 minutes)

Trial Site Locations

Total: 1 location

1

University of Coloardo Denver

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

D

David Calabrese

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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