Actively Recruiting

Phase 1
Phase 2
Age: 21Years +
FEMALE
NCT06845540

Oral Metformin for Treating Melasma in Latin American Women

Led by University of Puerto Rico · Updated on 2025-02-25

30

Participants Needed

1

Research Sites

14 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if metformin can treat melasma in Latin American women. The main question it aims to answer is: \- Can metformin help reduce the dark patches of melasma? Researchers will test two different doses of metformin (500 mg and 1000 mg) to see if either one helps improve melasma. Participants will: * Take a metformin pill every day for three months. * Go to the clinic twice: once at the beginning and once at the end of the study. * Get a phone call from the researchers to check how they're doing and ask about any changes or side effects.

CONDITIONS

Official Title

Oral Metformin for Treating Melasma in Latin American Women

Who Can Participate

Age: 21Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Latin American women aged 21 years or older
  • Diagnosed with epidermal or mixed melasma
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Use of hydroquinone or tretinoin within 2 months before the study
  • Undergoing laser treatment, chemical peels, microdermabrasion, or microneedling within 2 months before the study
  • History of kidney or liver disease
  • Allergy to metformin
  • Diabetes or hypoglycemia
  • Use of medications that may interact with metformin

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Administración de Servicios Médicos (ASEM) Clinicas Externas

San Juan, PR, Puerto Rico, 00935

Actively Recruiting

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Research Team

C

Cristina Brau

CONTACT

C

Camila Cordero

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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