Actively Recruiting
Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering
Led by University of Michigan · Updated on 2026-04-29
50
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to study the activity and connections within brain areas involved in speech production in adults who stutter. The focus is on examining how different parts of the brain work together during continuous speech in people with developmental stuttering. The study is sponsored by the University of Michigan and involves adults aged 18 to 65 years who currently stutter and speak English as their primary language. Participants will complete a speech production task with two conditions: stuttered and non-stuttered speech. This task will be performed while undergoing functional magnetic resonance imaging (MRI) to measure brain activity. The speaking task is the intervention studied, and the MRI serves as a tool to observe changes in brain signals during speech. The study includes multiple MRI visits over a period of up to 12 months from enrollment. During the study, researchers will measure brain activity by tracking changes in Blood-Oxygen-Level-Dependent (BOLD) signals during speech tasks conducted in five runs lasting eight minutes each, distributed across six MRI visits. Participants will be monitored for changes in brain function related to speech production. The total time commitment may extend up to a year, and all assessments involve non-invasive imaging and speech tasks to evaluate brain function.
CONDITIONS
Brief Title
Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Are between the ages of 18-65 years
- Have normal speech, language, hearing, and cognition
- Speak English as their primary language
- Currently stutter
You will not qualify if you...
- Have serious medical or neurological conditions such as stroke, traumatic brain injury, or Parkinson's disease
- Have had a closed head injury like a concussion
- Have a reading disorder such as dyslexia
- Have hearing loss
- Have metal or electronic implants such as cochlear implants or pacemakers
- Are currently pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 12 months from enrollment
Participants complete a speech production task during functional MRI sessions to assess brain activity related to stuttering and non-stuttering speech conditions.
6 MRI visits with speech tasks (5 runs, 8 minutes each)
Trial Site Locations
Total: 1 location
1
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
Research Team
E
Emily Garnett, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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