Actively Recruiting
Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2026-04-17
280
Participants Needed
9
Research Sites
393 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to learn about the impact of the different types of pain and of the domains involved in the autonomic disorders of inpatients and outpatients diagnosed with Parkinson disease (PD) and multiple system atrophy (MSA) admitted to Istituti Clinici Scientifici Maugeri Centers. The main aims are: Evaluate the prevalence of pain and characterize it in Parkinson's disease and atypical parkinsonisms (MSA) Evaluate the effect of rehabilitation on pain and autonomic symptoms Evaluate the prevalence of autonomic symptoms in Parkinson's disease and atypical parkinsonisms (MSA) Assess the impact of pain and autonomic symptoms on quality of life. Participants will perform neurological examination, rehabilitation program and clinical scales. Researchers will compare the two groups of patients (PD and MSA) and the effect of the rehabilitation on pain, autonomic symptoms and quality of life.
CONDITIONS
Official Title
Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of Parkinson's Disease or Multiple System Atrophy according to current international criteria
- Mini-Mental State Examination score at least 10
You will not qualify if you...
- Vascular or pharmacological parkinsonism
- Diabetes mellitus
- Hepatic or renal dysmetabolism
- Hypothyroidism or hyperthyroidism
- Use of potentially neurotoxic drugs
AI-Screening
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Trial Site Locations
Total: 9 locations
1
ICS Maugeri - IRCCS of Telese Terme
Telese Terme, Benevento, Italy, 82037
Actively Recruiting
2
ICS Maugeri - Lumezzane
Lumezzane, Brescia, Italy, 25065
Actively Recruiting
3
ICS Maugeri - Castelgoffredo
Castel Goffredo, Mantova, Italy, 46042
Actively Recruiting
4
ICS Maugeri - Mistretta
Mistretta, Messina, Italy, 98073
Actively Recruiting
5
ICS Maugeri - Veruno
Veruno, Novara, Italy, 28010
Actively Recruiting
6
ICS Maugeri - Montescano
Montescano, Pavia, Italy, 27040
Actively Recruiting
7
ICS Maugeri - Milano
Milan, Italy, 20138
Actively Recruiting
8
ICS Maugeri - Pavia Boezio
Pavia, Italy, 27100
Actively Recruiting
9
ICS Maugeri - Pavia
Pavia, Italy, 27100
Actively Recruiting
Research Team
M
Maria Nolano, MD, PhD
CONTACT
G
Giuseppe Caporaso
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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