Actively Recruiting
Parents Helping Parents for Youth Vaping Cessation (PhP-VX)
Led by University of Nebraska · Updated on 2026-05-26
200
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
Sponsors
U
University of Nebraska
Lead Sponsor
M
Massachusetts General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating a new program called Parents-helping-Parents for Youth Vaping Cessation (PhP-VX) to help adolescents aged 15 to 18 quit vaping. This randomized controlled study aims to test if the program, which includes peer support for parents delivered by trained coaches, is feasible and helpful. The study will involve 100 parent-adolescent pairs recruited through an electronic health record system and will compare the program against no treatment control. The PhP-VX program has two main parts: online lessons for parents and adolescents, and six bi-weekly, 30-minute, one-on-one coaching sessions for parents via Zoom. Parents in the program will receive guidance on identifying needs, communication skills, motivation, and goal setting to support their teens. Parents can also contact coaches for extra support. The control group will receive no treatment during the 3-month intervention but will get access to online materials after the study ends. Participants will complete surveys at baseline, and at 1, 3, and 6 months to track vaping behavior, knowledge, and exposure to marketing. A subset of 20 adolescents may provide saliva samples at these time points to measure cotinine levels, a marker for nicotine exposure, to verify self-reported vaping abstinence. The primary outcome is 7-day vaping abstinence, with secondary outcomes including vaping frequency, intensity, and other tobacco use. The study lasts six months with continued follow-up for all participants.
CONDITIONS
Brief Title
Parents Helping Parents for Youth Vaping Cessation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adolescents aged 15 to 18 years
- Reported vaping in the previous 30 days
- Able to read and understand English
- Parent or adult guardian is biological, adoptive, stepparent, or legal guardian of the adolescent
- Parent has face-to-face contact with the adolescent at least one day per week during the study
- Parent has access to a computer or mobile phone at home
- Parent is interested in helping the adolescent quit vaping
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person or remote)
Duration - 3 months
Participants in the test group receive the PhP-VX program consisting of online lessons for parents and adolescents and six bi-weekly, 30-minute one-on-one coaching sessions for parents. Participants in the control group do not receive treatment during this period.
Six bi-weekly coaching sessions via Zoom for parents in the test group
Duration - 3 additional months following treatment
All participants complete surveys assessing vaping behavior, knowledge, and media literacy at months 1, 3, and 6. A subset of adolescent participants may provide saliva samples at baseline, 3 months, and 6 months for biochemical verification of tobacco abstinence.
Surveys at months 1, 3, and 6; saliva sample collection at baseline, 3, and 6 months for a subset
Trial Site Locations
Total: 1 location
1
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198-4375
Actively Recruiting
Research Team
D
Daisy Dai, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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