Actively Recruiting
Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer
Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2024-12-03
40
Participants Needed
1
Research Sites
534 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators want to have a collection of fresh primary or recurrent tumor tissue for establishment of patients-derived xenografts in order to: generate a biobank of in vivo patient xenografts representing the different subgroups of tumors for head and neck cancer * perform genetic and transcriptional profiling of the primary, metastatic tumors and xenograft tumors * evaluate the efficacy of new targeted agents, whether or not in combination with standard treatment options * evaluate biomarkers of drug sensitivity * study primary and secondary (acquired) resistance in these models
CONDITIONS
Official Title
Patient-derived Xenograft Models of Tumor From Patients With Head and Neck Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with primary or recurrent/metastatic head and neck cancer can be included before surgery or tumor biopsy
- Data on tumor stage, grade, histology, adjuvant treatment, responses, and relapse must be available
- Follow-up data after treatment should be available
- Patients with recurrent disease are allowed
- Written informed consent is required
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Actively Recruiting
Research Team
A
Aline Gillain, MedSciences
CONTACT
S
Sandra Schmitz, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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