Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07444658

Performance of Two Daily Disposable Multifocal Contact Lenses

Led by CooperVision International Limited (CVIL) · Updated on 2026-04-08

35

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

C

CooperVision International Limited (CVIL)

Lead Sponsor

U

University of California, Berkeley

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating two designs of daily disposable multifocal soft contact lenses in people with presbyopia. This randomized, double-masked crossover study aims to compare the performance of these lenses when worn in real-world conditions. Participants will use each lens type for about one week to help understand their visual experience with each product. Participants will wear one type of daily disposable multifocal contact lens in both eyes for a period of 5 to 7 days, then switch to the other lens type for another 5 to 7 days. The study includes two groups: one starts with Lens A (kalfilcon A) and then crosses over to Lens B (stenfilcon A), while the other group follows the opposite order. Both lenses are soft daily disposables worn for one week each. During the study, participants' subjective visual acuity will be assessed approximately four hours after lens wear to evaluate their vision quality with each lens type. The study involves a total participation time of about two weeks, with careful monitoring to compare the lenses' performance. Participants will be evaluated throughout the study to capture their visual experience and any issues during lens wear.

CONDITIONS

Brief Title

Performance of Two Daily Disposable Multifocal Contact Lenses

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be at least 18 years old.
  • Participants must understand their rights and be willing to sign informed consent.
  • Participants must habitually use soft contact lenses (multifocal, monovision, or sphere lenses) at least 3 days a week for the past six months.
  • Participants must have a minimum reading addition of +0.75 diopters based on their spectacle prescription.
  • Participants must have a spherical equivalent refractive error between +6.00 to -10.00 diopters and astigmatism no greater than -0.75 diopters in each eye.
  • Participants must be able to achieve distance visual acuity of +0.10 logMAR or better in each eye.
Not Eligible

You will not qualify if you...

  • Participants with any ocular disorder that contraindicates contact lens wear.
  • Participants with systemic disorders that contraindicate contact lens wear.
  • Participants who are aphakic.
  • Participants who have had corneal refractive surgery.
  • Participants with corneal distortion from previous hard or rigid lens wear or with keratoconus.

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Implementation

Duration - Approximately 2 weeks

Participants wear two different designs of daily disposable soft multifocal contact lenses, each for 5 to 7 days in a randomized crossover design.

2 visits (in-person)

Trial Site Locations

Total: 1 location

1

University of California, Berkeley

Berkeley, California, United States, 94720

Actively Recruiting

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Research Team

J

Jose A Vega, OD,MSc,PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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