Actively Recruiting

Phase Not Applicable
All Genders
ID07021092

Person-Centered Approaches to Viremia: Connection, Rapport, and Engagement Study

Led by Centre for Infectious Disease Research in Zambia · Updated on 2025-06-13

3000

Participants Needed

2

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating person-centred approaches to improve engagement and connection for people living with HIV who face challenges in maintaining viral suppression. The study focuses on populations in Zambia who are most affected by viremia, including pregnant and breastfeeding women, children, adolescents, and adults who are more than 30 days late for their hospital appointments. The research aims to identify barriers to sustained viral suppression and develop tailored strategies to address these obstacles in vulnerable groups. The study will take place over 36 months in 24 healthcare facilities across Lusaka and Central provinces in Zambia. Interventions will be co-created with stakeholders using Human Centred Design methods to develop a person-centred package that improves patient connection, rapport, and engagement in care. This package will be tested specifically among high-priority populations contributing to ongoing viremia. Participants will be monitored for updated estimates of viremia and care status over a two-year period. The study involves tracing patients who are lost to follow-up or have elevated viral loads, assessing their care status and viral suppression outcomes. Written informed consent will be obtained, and participants will be followed to evaluate the impact of the person-centred interventions on viral load suppression and sustained engagement in care.

CONDITIONS

Brief Title

PERSON-CENTERED APPROACHES TO VIREMIA: CONNECTION, RAPPORT, AND ENGAGEMENT STUDY

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients lost to follow-up from HIV care, confirmed more than 30 days late for a scheduled appointment at sampling
  • Individuals returning to care after being out of care and not taking ART with no viral load measurement
  • Patients 6 months late for a scheduled viral load test according to Ministry of Health guidelines at sampling
  • Patients with last documented viral load greater than 1000 copies/ml at time of sampling
  • Participants willing to provide written informed consent in English, Nyanja, or Bemba
Not Eligible

You will not qualify if you...

  • Patients unable or unwilling to provide consent to participate
  • Individuals not living with HIV/AIDS
  • Patients too sick to participate (e.g., unable to talk, in general discomfort, or emergency cases)

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Intervention

Duration - Duration of the study follow-up period

Participants receive a person-centred package designed to connect them to service delivery, build rapport, and improve engagement in care to help achieve sustained viral load suppression.

Follow-up

Duration - 2 years

Participants are observed to assess updated estimates of viremia and care status over a 2-year period.

Trial Site Locations

Total: 2 locations

1

Ministry of Health

Lusaka, Lusaka Province, Zambia, 10101

Not Yet Recruiting

2

Railway GRZ Urban Health Centre, Kafue District Health Hospital, Nangongwe OPD Urban Health Centre, Chawama 1st level hospital, Chipate 1st level hospital, Matero Reference Health Centre, Mtendere Health Centre, Lwiimba Rural Health Centre

Lusaka, Lusaka Province, Zambia, 10101

Actively Recruiting

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Research Team

K

Kombatende Sikombe

D

Dr Sikazwe

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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