Actively Recruiting

Age: 6Years - 18Years
All Genders
ID06984679

Comparison of Dyspnea, Functional Capacity, Muscle Strength, Urinary Incontinence and Quality of Life Between Children and Adolescents With Cystic Fibrosis and Healthy Children

Led by Izmir Democracy University · Updated on 2026-03-27

50

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are comparing physical impairments such as urinary incontinence, breathing difficulty (dyspnea), muscle strength, functional capacity, and quality of life between children and adolescents with cystic fibrosis and healthy peers. The study aims to better understand how cystic fibrosis affects these health aspects and to support improvements in managing the condition. Participants include two groups: children and adolescents with cystic fibrosis and healthy children and adolescents. Both groups will undergo face-to-face evaluations lasting 45 to 60 minutes, which include clinical assessments, exercise tests, questionnaires, and measurements of breathing, muscle strength, and urinary incontinence. During the study, researchers will measure hand grip strength as the primary outcome over about one year. Secondary outcomes include assessments of breathing difficulty, lung function, respiratory and cough strength, aerobic and anaerobic exercise capacity, quality of life, and urinary incontinence scores. Participants will be monitored through these evaluations to gather comprehensive data on their physical health.

CONDITIONS

Brief Title

Physical Impairments in Children With Cystic Fibrosis

Who Can Participate

Age: 6Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages between 6 and 18 years
  • Diagnosed with cystic fibrosis (for the cystic fibrosis group)
  • Clinically stable for at least 3 weeks (for the cystic fibrosis group)
  • Necessary cooperation for the measurements
  • Volunteer to participate
  • Similar age and gender distribution as cystic fibrosis group (for healthy children group)
Not Eligible

You will not qualify if you...

  • Orthopedic, neurological, psychological, or cardiovascular problems preventing measurements in the last 6 months
  • Smoking or quitting smoking
  • Having any chronic disease (for healthy children group)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 visit

Participants undergo face-to-face physical evaluations including assessments of dyspnea, functional capacity, muscle strength, urinary incontinence, and quality of life.

1 visit (in-person lasting 45-60 minutes)

Long-term Monitoring

Duration - Approximately 1 year

Participants are observed through assessments of hand grip strength, dyspnea score, pulmonary function, respiratory and cough strength, exercise capacity, quality of life, and urinary incontinence over about 1 year.

Assessments conducted periodically through study completion

Trial Site Locations

Total: 1 location

1

Izmir Democracy University

Izmir, Turkey (Türkiye), 35140

Actively Recruiting

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Research Team

G

Gülşah Barğı, Assoc Prof

Y

Yağmur Külekçi, PT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Frequently Asked Questions

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Published Research Related To This Trial

Trajectories of urinary incontinence in childhood and bladder and bowel symptoms in adolescence: prospective cohort study.

Jon Heron, Mariusz T Grzeda, Alexander von Gontard...

https://pubmed.ncbi.nlm.nih.gov/28292756