Study of Using Ileostomy Infusion Before Surgery to Help Intestine Recover Faster After Stoma Reversal

What this Trial Is About

This research study focuses on people with a diverting loop ileostomy who are preparing for a stoma takedown operation, which reconnects the intestine after a period of diversion. Because the part of the intestine past the ileostomy has not processed intestinal content for weeks to months, it may take time to regain normal function after surgery. The study aims to see if infusing the contents from the ostomy bag back into the intestine before surgery can help retrain it and speed up bowel recovery. Participants will be randomly assigned to one of two groups one group will receive antegrade infusion of ileostomy contents back into their intestine before surgery, while the other group will not receive this intervention. The infusion is planned to be performed prior to the stoma takedown operation to simulate normal intestinal activity. The study is designed as a double-blind, randomized trial and includes phases 1 and 2. During the study, researchers will monitor how quickly bowel function returns after surgery, measuring the timing within 1 to 5 days. They will also track how easy it is to perform the stoma infusion from two weeks before surgery until the time of surgery, and monitor any complications from two weeks before surgery through 30 days after the operation. Participants will be followed throughout this period to assess safety and effectiveness of the intervention.

Pilot Study of Preoperative Intestinal Training Using Antegrade Ileostomy Infusion