Actively Recruiting

Age: 65Years - 90Years
All Genders
NCT06182215

PostoperAtive Neurocognitive Dysfunction After Major AbdomiNal Surgery (PANDAMAN)

Led by Sixth Affiliated Hospital, Sun Yat-sen University · Updated on 2024-06-17

500

Participants Needed

1

Research Sites

159 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Predisposing and precipitating factors for perioperative delirium for the elderly remain elusive. This research will be conducted to determine risk factors of postoperative delirium.

CONDITIONS

Official Title

PostoperAtive Neurocognitive Dysfunction After Major AbdomiNal Surgery (PANDAMAN)

Who Can Participate

Age: 65Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 65 and 90 years
  • Scheduled for elective major abdominal surgery expected to last over 2 hours
  • American Society of Anesthesiologists (ASA) physical status classification I to III
Not Eligible

You will not qualify if you...

  • Mini-Mental State Examination (MMSE) score less than 15
  • Renal failure requiring dialysis or liver failure with Child-Pugh score greater than 5
  • Severe brain injury or impairment due to structural or hypoxic causes
  • More than 2 days spent in ICU within one month before surgery
  • Major heart, lung, or abdominal surgery within the past year
  • Positive for SARS-CoV-2 or symptomatic for COVID-19
  • Unable to complete cognitive assessment due to blindness, deafness, or language barriers
  • Unavailable for long-term follow-up due to homelessness, active psychosis, or substance abuse

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Sixth Affiliated Hospital of Sun Yet-set University

Guangzhou, Guangdong, China, 510100

Actively Recruiting

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Research Team

X

Xiangcai Ruan, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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