Actively Recruiting
Patient Registry for Women Diagnosed With Preterm Premature Rupture of Membranes or PPROM During Pregnancy
Led by American Alliance for pProm Support · Updated on 2026-03-16
3000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to better understand pregnancies and births affected by Preterm Premature Rupture of Membranes (PPROM), a condition responsible for 40% of preterm births in the United States. It focuses on identifying possible causes of PPROM, reviewing how it is managed during pregnancy, and evaluating maternal and fetal care. The study also examines both short-term and long-term outcomes for pregnancies and babies impacted by PPROM, addressing gaps in previous research with small sample sizes and limited follow-up. This is an observational patient registry study with no intervention or treatment assigned. It collects data on how PPROM is managed before 37 weeks of pregnancy, including expectant management versus immediate delivery options. The registry also gathers information on neonatal care in the intensive care unit and tracks trends in treatment approaches and outcomes. Participants will be monitored through data collection of pregnancy and birth outcomes, including early neonatal mortality up to 28 days after delivery and stillbirth or perinatal mortality at delivery. The study provides long-term follow-up to better understand the effects of PPROM on mothers and babies. Participation involves sharing medical information without receiving a specific study treatment, with the study lasting for several years to capture comprehensive outcomes.
CONDITIONS
Brief Title
PPROM Registry (Preterm Premature Rupture of Membranes)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women diagnosed with Preterm Premature Rupture of Membranes (PPROM) prior to 37 weeks of pregnancy
You will not qualify if you...
- Those without a clinical diagnosis or confirmation of PPROM in pregnancy
- Diagnosis of PROM beyond 37 weeks of pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - From diagnosis until delivery and neonatal period
Participants who are diagnosed with Preterm Premature Rupture of Membranes (PPROM) are observed to understand pregnancy management, delivery, and neonatal care outcomes.
Visits and assessments occur as part of clinical care during pregnancy and after delivery depending on clinical need.
Trial Site Locations
Total: 1 location
1
Www.Aapprom.Org/the-Registry
Denver, Colorado, United States, 80202
Actively Recruiting
Research Team
E
Erin Thatcher
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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