Actively Recruiting
Precision Medicine in the Depression Treatment
Led by Rigshospitalet, Denmark · Updated on 2024-10-08
800
Participants Needed
1
Research Sites
285 weeks
Total Duration
On this page
Sponsors
R
Rigshospitalet, Denmark
Lead Sponsor
M
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The BrainDrugs-D study uses multimodal neuroimaging combined with self-report measures, clinical and molecular markers to identify clinically relevant predictors that can identify subtypes of major depressive disorder (MDD) and, in a naturalistic setting, predict treatment response to standard antidepressive treatment. The cohorts are followed in nationwide health registries.
CONDITIONS
Official Title
Precision Medicine in the Depression Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Diagnosis of a primary depressive episode according to International Classification of Diseases version 10
- Referral to a treatment package for single-episode depression
You will not qualify if you...
- Psychosis or psychotic symptoms
- History of severe head trauma
- Somatic disease causing brain changes (e.g., brain tumor)
- Insufficient Danish language skills to complete questionnaires and cognitive testing
- For Cohort II: Severe somatic disease or contraindications for MRI (e.g., metal implants, claustrophobia, back problems)
- For Cohort III: Severe somatic disease, contraindications for MRI, recent exposure to radioactivity over 10 mSv, pregnancy or breastfeeding, use of psychotropic drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Neurobiology Research Unit, Rigshospitalet
Copenhagen, Denmark, 2100
Actively Recruiting
Research Team
K
Kristian HR Jensen, MD
CONTACT
M
Martin B Jørgensen, DMSc
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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