Actively Recruiting
Intervening Quickly: A Pilot Randomized Controlled Trial to Improve Cognitive Processing Speed in Acute Spinal Cord Injury
Led by Kessler Foundation · Updated on 2024-06-06
24
Participants Needed
3
Research Sites
26 weeks
Total Duration
On this page
Sponsors
K
Kessler Foundation
Lead Sponsor
C
Craig Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether a cognitive training program can improve processing speed in individuals who have recently experienced an acute traumatic spinal cord injury (SCI). This pilot randomized controlled trial aims to address cognitive difficulties such as attention, memory, and information processing speed, which can significantly impact rehabilitation outcomes and quality of life. The study focuses on early intervention to potentially enhance overall health and well-being for people with acute SCI. Participants are randomly assigned to one of two groups: an experimental group or a placebo control group. Both groups complete pre-specified game-like computerized tasks using an internet-based cognitive training portal. These sessions occur three times per week, lasting 60 minutes each, over a total of 12 weeks. The study uses a quadruple masking design to reduce bias. During the study, participants undergo assessments at baseline, immediately after treatment (week 13), and at long-term follow-up (week 25). Researchers measure processing speed using tests such as the Useful Field of View (UFOV), Letter & Pattern Comparison (LPC), and Symbol Digit Modalities Test (SDMT). Quality of life related to spinal cord injury is also evaluated. The total participation period spans approximately six months, including treatment and follow-up evaluations.
CONDITIONS
Brief Title
A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 59 years old
- Recent traumatic spinal cord injury, approximately within 6 months post-injury
You will not qualify if you...
- History of significant neurological, psychiatric, or substance use disorders
- Significant vision problems that impair daily activities
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants complete pre-specified computer tasks using an Internet-based cognitive training portal, 3 times per week for 60 minutes each session over 12 weeks.
Regular sessions at home 3 times per week
Duration - 12 weeks
Participants are assessed for cognitive processing speed and quality of life after treatment and at long-term follow-up.
2 visits (at week 13 and week 25)
Trial Site Locations
Total: 3 locations
1
Craig Hospital
Englewood, Colorado, United States, 80113
Actively Recruiting
2
Kessler Foundation
East Hanover, New Jersey, United States, 07936
Actively Recruiting
3
University of Washington
Seattle, Washington, United States, 98105
Not Yet Recruiting
Research Team
E
Erica Weber
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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