Actively Recruiting
Prediction and Intervention Effect of Rehabilitation Status for Severe Mental Disorder Patients Based on Multimodal Analysis and AI Agents
Led by Shanghai Mental Health Center · Updated on 2025-08-17
82
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
S
Shanghai Mental Health Center
Lead Sponsor
S
Shanghai Jiao Tong University School of Medicine
Collaborating Sponsor
AI-Summary
What this Trial Is About
Mental health problems significantly affect many areas of life, including psychological, social, work, and education functions, especially in people with severe mental disorders. These disorders often follow a long-term course with reduced social ability and isolation, making it hard for patients to reintegrate into society. This research explores new digital rehabilitation approaches using multimodal technology, reinforcement learning, and agent-based modeling to better assess and support mental health recovery in patients with severe mental disorders. The study involves developing and testing a gamified digital rehabilitation intervention combined with standard pharmacological treatment and community rehabilitation services. Participants in the intervention group will engage in structured story-based digital games focusing on medication management and psychological rehabilitation five times per week for 30 minutes each session over three months. A control group will receive routine care including regular medication and community support. The research includes multiple phases: theoretical groundwork, designing and evaluating gamified interventions through a randomized controlled trial, multimodal data analysis, and applying AI models to predict and optimize rehabilitation outcomes. Participants will be monitored at baseline, immediately after the three-month intervention, and at one, three, and six months follow-up. Researchers will assess various outcomes such as symptom severity, medication adherence, anxiety, depression, quality of life, and social functioning. Data from game behavior, physiological and psychological measures will be collected to track rehabilitation progress and guide treatment decisions. The study aims to provide a comprehensive and personalized approach to mental health rehabilitation while ensuring ethical standards and privacy.
CONDITIONS
Brief Title
Prediction and Intervention Effect of Rehabilitation Status for Severe Mental Disorder Patients Based on Multimodal Analysis and AI Agents
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Registered in the Shanghai Mental Health Information Management System
- Diagnosed with one of six severe mental disorders: schizophrenia, schizoaffective disorder, paranoid psychosis, bipolar disorder, mental disorder due to epilepsy, or mental retardation with mental disorder
- Aged between 18 and 65 years
- Have normal or corrected vision and hearing
- Provided informed consent (patient or family) and signed consent form
You will not qualify if you...
- Having severe physical illnesses
- Having organic brain diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 3 months
Participants receive either a gamified digital rehabilitation intervention combined with routine pharmacological treatment and community rehabilitation services, or routine pharmacological treatment and standard community rehabilitation services alone.
Digital rehabilitation games 5 times per week (30 minutes each) during treatment period; routine care visits as per community rehabilitation schedule
Duration - 6 months
Participants are monitored for rehabilitation status and assessed through follow-up visits to evaluate the lasting effects of the intervention.
1-month, 3-month, and 6-month follow-up visits after treatment completion
Trial Site Locations
Total: 1 location
1
Shanghai Mental Health Center
Shanghai, China
Actively Recruiting
Research Team
W
Weibo Zhang
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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