Short-term outcomes after selective shunt during carotid endarterectomy: a propensity score matching analysis.
Juliana Pereira-Macedo, Luís Duarte-Gamas, António Pereira-Neves...
https://pubmed.ncbi.nlm.nih.gov/37696419/Actively Recruiting
Led by Universidade do Porto · Updated on 2020-04-15
206
Participants Needed
1
Research Sites
521 weeks
Total Duration
This research aims to identify factors that predict neurologic deficits occurring during carotid endarterectomy CEA with regional anesthesia, a procedure for carotid artery stenosis. It addresses the risk of neurologic problems caused by reduced brain blood flow during carotid artery clamping and the related risk of stroke after surgery. The study also examines the effects of these neurologic deficits around the time of surgery. The study observes patients who undergo carotid endarterectomy performed with regional anesthesia. It compares patients who experience neurologic changes after the artery is clamped with those who do not have such changes. All patients come from a tertiary referral center, and the control group is selected in a 1 to 1 ratio with the affected patients. Participants are monitored for neurologic symptoms during and after surgery. The main outcome being measured is the occurrence of stroke within five years after the procedure. Secondary outcomes include serious postoperative complications classified by the Clavien-Dindo scale within 30 days. Researchers evaluate medical records and neurologic exams to assess risks and consequences of neurologic deficits related to the surgery.
CONDITIONS
Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia
J
Joao P Rocha-Neves, MD, MSC; MPH, FEBVS
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Universidade do Porto
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants undergo carotid endarterectomy with regional anesthesia and are observed for neurologic deficits during carotid cross-clamping and immediate post-operative recovery.
1 surgery day with immediate post-operative observation
Duration - Up to 5 years
Participants are followed up to monitor for stroke and other complications after surgery.
Follow-up visits as scheduled over 5 years
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Juliana Pereira-Macedo, Luís Duarte-Gamas, António Pereira-Neves...
https://pubmed.ncbi.nlm.nih.gov/37696419/José D Vieira-Andrade, João P Rocha-Neves, Juliana P Macedo...
https://pubmed.ncbi.nlm.nih.gov/31382007/Juliana Pereira-Macedo, João P Rocha-Neves, Marina F Dias-Neto...
https://pubmed.ncbi.nlm.nih.gov/31542388/Universidade do Porto
Lead Sponsor