Monitoring Brain Oxygen Levels During Carotid Endarterectomy to Predict Postoperative Delirium A Prospective Study

What this Trial Is About

Postoperative delirium POD is a common complication seen after surgery, especially in elderly patients undergoing carotid endarterectomy CEA. These patients often have vascular risks, cognitive issues, or a history of stroke, which combined with fluctuating blood flow during surgery can lead to reduced oxygen supply to brain tissue. This trial aims to study how changes in local cerebral oxygen saturation SctO2 during surgery relate to the development of POD and to find the SctO2 levels that predict POD in this high-risk group. The study observes patients undergoing CEA and continuously monitors their brain oxygen levels using Near-infrared Spectroscopy NIRS during surgery. This device noninvasively measures the oxygen saturation in cerebral tissue to detect any imbalance between oxygen supply and demand. No treatments are assigned instead, the study gathers data on SctO2 changes throughout the operation to understand their association with postoperative delirium. Participants will be followed for five days after surgery to monitor and record any signs of postoperative delirium. Researchers will collect and analyze these data to evaluate the relationship between intraoperative oxygen saturation and POD occurrence. This prospective cohort study is sponsored by Beijing Tiantan Hospital and is expected to end in December 2025.

Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy