Actively Recruiting
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy
Led by Beijing Tiantan Hospital · Updated on 2025-02-13
140
Participants Needed
1
Research Sites
202 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive dysfunction, some also had a history of stroke, and the circulation fluctuated greatly during the operation, often resulting in hypoperfusion of cerebral tissue and hypoxia. Therefore, they're the high-risk group of POD. Near-infrared Spectroscopy (NIRS) can continuously and noninvasively monitor local cerebral oxygen saturation (SctO2) to identify the mismatch of oxygen supply and demand in brain tissue. However, for CEA patients, the association between intraoperative SctO2 changes and POD remains unclear. This study intends to explore the association between them and determine the SctO2 threshold for predicting POD. We will monitor SctO2 intraoperatively, follow up and collect data postoperatively.
CONDITIONS
Official Title
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled carotid endarterectomy
- Signed informed consent
You will not qualify if you...
- Severe cognitive impairment (Mini-Mental State Examination score below 18)
- History of psychotropic drug use
- Previous intracranial surgery
- Poor hearing or vision
- Language barriers
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beijing Tian Tan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100160
Actively Recruiting
Research Team
Y
Yuming MD Peng, Ph.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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