Epidemiological study of psoriasis in the national health insurance database in Taiwan.
Yun-Ting Chang, Tzeng-Ji Chen, Pei-Chi Liu...
https://pubmed.ncbi.nlm.nih.gov/19479122Actively Recruiting
Age: 18Years +
All Genders
ID04950218
PSOCADIA: Prevalence and Risk Factors Associated With Cardiac Comorbidity in Psoriasis
Led by Herlev and Gentofte Hospital · Updated on 2025-09-15
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the link between heart-related biomarkers and advanced heart ultrasound techniques to find out if they can predict heart disease in people with psoriasis. Psoriasis and cardiovascular disease both involve chronic inflammation, and previous studies suggest that psoriasis may increase the risk of heart problems like heart attacks and strokes. This study focuses on a group of 1,000 psoriasis patients and a control group to understand these connections better. The study includes a comprehensive examination of psoriasis patients recruited from outpatient clinics, along with a control group from previous population studies. Participants will undergo physical exams, blood tests for specific biomarkers, and advanced heart ultrasound scans to detect subtle heart dysfunction. Blood samples may also be stored for future research. The study will follow participants for 2, 5, and 10 years to track heart-related outcomes such as heart attacks, revascularizations, and cardiovascular deaths. Participants will provide medical history, lifestyle information, and undergo assessments like psoriasis severity scoring, blood pressure, and ECG. Researchers will collect and analyze data on heart function, biomarker levels, and health events over time. The primary outcomes include cardiovascular mortality and heart attacks, while secondary outcomes cover all-cause mortality, heart failure hospitalizations, and strokes. Data will be securely stored and analyzed to identify early signs of heart disease in psoriasis patients and improve understanding of inflammation's role in heart conditions.
CONDITIONS
Brief Title
Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patients 18 years or older with a diagnosis of psoriasis will be invited to participate
You will not qualify if you...
- Patients not able to cooperate to the study
- Patients unable understand and sign informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - At inclusion
Participants undergo comprehensive baseline assessments including questionnaires, physical exams by a dermatologist, blood sample collection for biomarkers, and advanced echocardiographic imaging to evaluate heart function and psoriasis severity.
1 visit (in-person)
Long-term Monitoring
Duration - Up to 10 years
Participants are followed for up to 10 years with ongoing data collection on cardiovascular events, hospitalizations, and mortality through national registries to assess long-term cardiac outcomes related to psoriasis.
Follow-up assessments at 2, 5, and 10 years
Trial Site Locations
Total: 1 location
1
Department of Cardiology, Herlev and Gentofte University Hospital, University of Copenhagen
Hellerup, Copenhagne, Denmark, 2900
Actively Recruiting
Loading map...
Research Team
M
Maria F Dons, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Psoriasis and diabetes: a population-based cross-sectional study.
A D Cohen, J Dreiher, Y Shapiro...
https://pubmed.ncbi.nlm.nih.gov/18331320Association between psoriasis and the metabolic syndrome. A cross-sectional study.
A D Cohen, M Sherf, L Vidavsky...
https://pubmed.ncbi.nlm.nih.gov/18216477Prevalence of metabolic syndrome in patients with psoriasis: a hospital-based case-control study.
P Gisondi, G Tessari, A Conti...
https://pubmed.ncbi.nlm.nih.gov/17553036Disease concomitance in psoriasis.
T Henseler, E Christophers
https://pubmed.ncbi.nlm.nih.gov/7751469Prevalence of cardiovascular risk factors in patients with psoriasis.
Andrea L Neimann, Daniel B Shin, Xingmei Wang...
https://pubmed.ncbi.nlm.nih.gov/17052489Dislipidemia and oxidative stress in mild and in severe psoriasis as a risk for cardiovascular disease.
P Rocha-Pereira, A Santos-Silva, I Rebelo...
https://pubmed.ncbi.nlm.nih.gov/11163020The association between psoriasis, diabetes mellitus, and atherosclerosis in Israel: a case-control study.
Jonathan Shapiro, Arnon D Cohen, Michael David...
https://pubmed.ncbi.nlm.nih.gov/17157411Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis.
Dorothea M Sommer, Stefan Jenisch, Michael Suchan...
https://pubmed.ncbi.nlm.nih.gov/17021763Cardiovascular risk profile of patients with psoriatic arthritis compared to controls--the role of inflammation.
L-S Tam, B Tomlinson, T T-W Chu...
https://pubmed.ncbi.nlm.nih.gov/18400833