Study of Heart Disease Risk and Cardiac Health in Adults with Psoriasis Using Biomarkers and Advanced Echocardiography

What this Trial Is About

Researchers are investigating the link between heart-related biomarkers and advanced heart ultrasound techniques to find out if they can predict heart disease in people with psoriasis. Psoriasis and cardiovascular disease both involve chronic inflammation, and previous studies suggest that psoriasis may increase the risk of heart problems like heart attacks and strokes. This study focuses on a group of 1,000 psoriasis patients and a control group to understand these connections better. The study includes a comprehensive examination of psoriasis patients recruited from outpatient clinics, along with a control group from previous population studies. Participants will undergo physical exams, blood tests for specific biomarkers, and advanced heart ultrasound scans to detect subtle heart dysfunction. Blood samples may also be stored for future research. The study will follow participants for 2, 5, and 10 years to track heart-related outcomes such as heart attacks, revascularizations, and cardiovascular deaths. Participants will provide medical history, lifestyle information, and undergo assessments like psoriasis severity scoring, blood pressure, and ECG. Researchers will collect and analyze data on heart function, biomarker levels, and health events over time. The primary outcomes include cardiovascular mortality and heart attacks, while secondary outcomes cover all-cause mortality, heart failure hospitalizations, and strokes. Data will be securely stored and analyzed to identify early signs of heart disease in psoriasis patients and improve understanding of inflammations role in heart conditions.

Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsis