Actively Recruiting

Age: 18Years +
All Genders
ID03113552

Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2023-05-23

1500

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Mitral insufficiency (MI) is a common heart valve problem that affects many adults, especially those over 75 years old. It is a leading cause of valve disease in Europe, often caused by mitral valve prolapse. This research observes how the location of mitral valve prolapse influences the long-term results after mitral valve repair surgery, which is the standard treatment for symptomatic MI. The study follows patients who underwent mitral valve surgery between 1988 and 2011. It investigates how the site of the prolapse—whether affecting one or both leaflets of the mitral valve—may impact surgical outcomes over time. The research collects data from clinical evaluations and echocardiography performed when the patients were initially diagnosed. Participants are monitored for survival, measured from the date of surgery until death or the last known follow-up within six months. The study assesses long-term outcomes based on valve geometry and prolapse location. No new treatments are given, and the study mainly involves reviewing past surgery cases and clinical records to understand prognosis.

CONDITIONS

Brief Title

Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients operated between 1988 and 2011
  • Presence of a valvular prolapse diagnosed by echocardiography
  • Possibility of a complete clinical evaluation at the time of the initial echocardiography
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Ischemic mitral insufficiency, including papillary muscle rupture
  • Significant aortic valvulopathy, mitral valvular stenosis, or congenital heart disease
  • History of cardiac surgery other than mitral valve repair

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 6 months after surgery

Participants who underwent mitral valve surgery are observed to assess survival and health outcomes over time.

Follow-up visits as scheduled based on clinical care

Trial Site Locations

Total: 1 location

1

CHU Amiens Picardie

Amiens, Picardie, France, 80054

Actively Recruiting

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Research Team

C

Catherine SZYMANSKI, Dr

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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