Actively Recruiting
PRospective Registry of Esophageal Motility
Led by IRCCS San Raffaele · Updated on 2026-04-02
10000
Participants Needed
1
Research Sites
781 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Digestive physiopathology is a branch of gastroenterology aiming to study patients with upper GI symptoms, mainly gastro-esophageal, potentially indicating the presence of Gastroesophageal Reflux Disease (GERD)/Barrett Esophagus (BE) or obstructive esophageal motility disorders (achalasia being the most relevant), but including also other primary motility disorders such as Esophgago-Gastric Junction Outflow Obstruction (EGJOO), Hypercontractile Esophagus (HE), Distal Esophageal Spasm (DES) and other minor disorders. Physiopathological testing encompasses High-Resolution Manometry (HRM), 24-H esophageal pH-impedance testing, Functional Lumen Imaging Probe (FLIP) assessment. All these tests are designed to provide a clear phenotyping of esophago-gastric disorders related to reflux or obstructive esophageal symptoms, either in naïve patients, as well as after foregut surgery (particularly anti-reflux surgery, achalasia/primary motility disorders treatment).
CONDITIONS
Official Title
PRospective Registry of Esophageal Motility
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant is willing and able to give informed consent for participation in the study.
- The procedures are the standard of care for the patient or the participant is taking the medicinal product according to clinical practice.
- Aged > 18 years.
- Have typical or atypical reflux symptoms or obstructive esophageal symptoms potentially reflecting motility disorders.
- Patients with esophageal inflammatory disorders or systemic rheumatological conditions.
- Patients who have undergone anti-reflux surgery, bariatric surgery, or esophageal/gastric myotomy.
- Patients must be referred to the Digestive Physiopathology Unit of IRCCS San Raffaele Hospital for motility tests.
You will not qualify if you...
- Age < 18 years.
- Not willing to provide informed consent to the inclusion in the registry.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS San Raffaele Hospital
Milan, Lombardy, Italy, 20132
Actively Recruiting
Research Team
A
Alberto Barchi, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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