Actively Recruiting

Age: 35Years - 70Years
All Genders
ID03225586

Prospective Urban Rural Epidemiology Study

Led by Population Health Research Institute · Updated on 2024-01-31

200000

Participants Needed

34

Research Sites

N/A

Total Duration

On this page

Sponsors

P

Population Health Research Institute

Lead Sponsor

C

Canadian Institutes of Health Research (CIHR)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying how individual health behaviors and broader societal factors like environment, policies, and health system quality affect health outcomes such as death and the development of chronic diseases. This study also explores genetic influences on non-communicable diseases through both a cross-sectional and a prospective cohort approach. It aims to understand these relationships across different socioeconomic and health resource settings worldwide. Participants are adults aged 35 to 70 years at enrollment. The study involves observing various health-related behaviors, societal determinants including built environment, food and nutrition policies, psychosocial and socioeconomic factors, and tobacco use. Researchers will track the incidence of chronic diseases like cardiovascular disease, cancer, respiratory conditions, diabetes, kidney disease, obesity, hypertension, and injuries over time, without administering any specific treatments. Participants will be followed for an average of 10 years, during which researchers will monitor health events such as new cases of cardiovascular disease and other illnesses, hospitalizations, and mortality. Data will be collected on genetic factors and changes in risk factors like smoking and diet. The study measures the impact of health systems and environmental influences on outcomes. Participants will be involved through regular assessments but will not receive interventions as this is an observational study.

CONDITIONS

Brief Title

Prospective Urban Rural Epidemiology Study

Who Can Participate

Age: 35Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Consenting adults between 35 and 70 years of age
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 10 years

Participants are observed over time to examine societal influences, health-related behaviors, and health outcomes including chronic diseases and mortality.

Periodic visits over 10 years

Trial Site Locations

Total: 34 locations

1

Estudios Clinicos Latinoamerica ECLA

Rosario, Santa Fe Province, Argentina

Actively Recruiting

2

Independent University, Bangladesh

Dhaka, Bangladesh

Actively Recruiting

3

Dante Pazzanese Institute of Cardiology

São Paulo, Brazil

Actively Recruiting

4

Simon Fraser University

Vancouver, British Columbia, Canada

Actively Recruiting

5

Population Health Research Institute

Hamilton, Ontario, Canada, L8L2X2

Actively Recruiting

6

University of Ottawa

Ottawa, Ontario, Canada, K1H8L6

Actively Recruiting

7

Université Laval Institut universitaire de cardiologie et de pneumologie de Québec

Québec, Quebec, Canada

Actively Recruiting

8

Universidad de La Frontera

Temuco, Chile

Actively Recruiting

9

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital

Beijing, China

Actively Recruiting

10

Fundacion Oftalmologica de Santander - FOSCAL

Floridablanca, Santander Department, Colombia

Actively Recruiting

11

St John's Research Institute

Bangalore, Karnataka, India

Actively Recruiting

12

Health Action by People

Thiruvananthapuram, Kerala, India

Actively Recruiting

13

Eternal Heart Care Centre and Research Institute

Jaipur, Rajasthan, India

Actively Recruiting

14

Madras Diabetes Research Foundation

Chennai, Tamil Nadu, India

Actively Recruiting

15

Post Graduate Institute of Medical Education and Research (PGIMER)

Chandigarh, India

Actively Recruiting

16

Isfahan University of Medical Sciences

Isfahan, Iran

Actively Recruiting

17

Research Institute of Cardiology & Internal Diseases

Almaty, Kazakhstan

Actively Recruiting

18

Kyrgyz Society of Cardiology, National Center of Cardiology and Internal Disease

Bishkek, Kyrgyzstan

Actively Recruiting

19

Universiti Teknologi MARA, UCSI Universiti

Kuala Lumpur, Malaysia

Actively Recruiting

20

University Kebangsaan Malaysia

Kuala Lumpur, Malaysia

Actively Recruiting

21

Aga Khan University

Karachi, Pakistan

Actively Recruiting

22

Birzeit University, Birzeit

Ramallah, Palestinian Territories

Actively Recruiting

23

Universidad Peruana Cayetano Heredia

Lima, Peru

Actively Recruiting

24

University of Philippines, Section of Adult Medicine & Medical Research Unit

Manila, Philippines

Actively Recruiting

25

Wroclaw Medical University & Department of Internal Medicine

Wroclaw, Poland

Actively Recruiting

26

Research Institute for Complex Issues of Cardiovascular Diseases

Kemerovo, Russia

Actively Recruiting

27

King Saud University

Riyadh, Saudi Arabia

Actively Recruiting

28

School of Public Health, University of the Western Cape

Bellville, South Africa

Actively Recruiting

29

North-West University

Potchefstroom, South Africa

Actively Recruiting

30

Sahlgrenska University Hospital/Östra Hospital

Gothenburg, Sweden

Actively Recruiting

31

Pamoja Tunaweza Women Center

Moshi, Tanzania

Actively Recruiting

32

Istanbul Medeniyet University

Istanbul, Turkey (Türkiye)

Actively Recruiting

33

Dubai Medical University

Dubai, United Arab Emirates

Actively Recruiting

34

University of Zimbabwe College of Health Sciences

Harare, Zimbabwe

Actively Recruiting

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Research Team

S

Sumathy Rangarajan, MSc

J

Janette Panhuis, BScN, MBA

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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The Prospective Urban Rural Epidemiology (PURE) study: examining the impact of societal influences on chronic noncommunicable diseases in low-, middle-, and high-income countries.

Koon Teo, Clara K Chow, Mario Vaz...

https://pubmed.ncbi.nlm.nih.gov/19540385

Environmental and societal influences acting on cardiovascular risk factors and disease at a population level: a review.

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https://pubmed.ncbi.nlm.nih.gov/19261658