Early Detection of Type 2 Diabetes and Cardiovascular Risks Using CUORE and FINDRISC Tools in Adults Turning 50 in Marche Region

What This Trial Is About

This research aims to test a new systematic screening program designed to detect early risk of type 2 diabetes mellitus T2DM and cardiovascular diseases CVDs in individuals aged 50 years living in the Ascoli Piceno province without prior diagnosis. The study uses CUORE and FINDRISC tools developed specifically for this project to assess 10-year risks. The screening will take place throughout 2026 at the Prevention Department locations in Ascoli Piceno and San Benedetto del Tronto within the Local Health Authority. The intervention involves inviting eligible individuals via letter to participate in the screening. Participants will book appointments through a regional system and attend the Prevention Department where healthcare professionals will explain the study, obtain consent, and collect questionnaire and sociodemographic data. Clinical parameters such as anthropometric measures, blood pressure, cholesterol, and HbA1c for higher risk FINDRISC scores will be collected using small medical devices and finger-prick tests. Based on risk scores, tailored prevention pathways will be suggested, and results may be added to participants electronic health records with consent. Participants will be followed up with phone calls at 3 and 6 months after screening to assess adherence to suggested pathways like visits to general practitioners or lifestyle counseling. Data collection will include clinical, questionnaire, and sociodemographic information. The main outcome is to evaluate screening adherence by coverage at the end of 2026, along with assessment of 10-year risk scores, risk detection rates, pathway adherence, and results according to participant characteristics.

"Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and Cardiovascular Diseases in the Marche Region"