Actively Recruiting
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
Led by Ohio State University · Updated on 2025-12-19
22
Participants Needed
2
Research Sites
168 weeks
Total Duration
On this page
Sponsors
O
Ohio State University
Lead Sponsor
V
Varian Medical Systems
Collaborating Sponsor
AI-Summary
What this Trial Is About
A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurgery dorsal rhizotomy." It uses very accurate beams of radiation to target certain nerves in the back to help loosen up the muscles. In this study, people are put into two groups by chance: one group gets the real treatment, and the other group gets a "fake" treatment that doesn't do anything. This fake treatment is called a "sham." Doing this helps make sure the study is fair and the results are true. After the people in the study get their treatment, the researchers will watch and see how they do. They will check if their muscles are less stiff and if they have any side effects. By looking at the results from both groups, the researchers can find out if the special treatment really helps people with spasticity. Patients who got the "fake" treatment will be eligible to receive the "real" treatment after 6 months.
CONDITIONS
Official Title
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chronic spasticity not improved by medical treatments or in patients unable to receive proper medical management affecting one or more spinal nerve roots
- Age 16 years or older (parental consent required if under 18)
You will not qualify if you...
- Unable to lie on back for simulation and treatment
- Target nerve not visible on CT or MRI imaging
- Confirmed pregnancy (women of child-bearing age must have pregnancy test before simulation)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Renaissance Institute of Precision Oncology & Radiosurgery
Winter Park, Florida, United States, 32789
Actively Recruiting
2
Ohio State University Wexner Medical Center
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
U
Uchechi Okafor, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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