Actively Recruiting

Age: 18Years +
All Genders
NCT07448181

Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdema

Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2026-03-04

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to conduct an in-depth analysis of the Burden of Disease (BoD) perceived by patients with Hereditary Angioedema (HAE), through daily prospective observations based on Ecological Momentary Assessment (EMA) via digital surveys and standardised questionnaires. Participants will answer online survey questions about their perceived burden of disease for 8 consecutive weeks. The main hypothesis is that daily prospective observation (EMA) will reveal a higher and more fluctuating burden of disease compared to traditional retrospective scales, providing a more accurate representation of the impact of HAE on patients' daily lives.

CONDITIONS

Official Title

Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdema

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of Type 1 or Type 2 hereditary angioedema
  • Age 18 years or older
  • Ability to understand instructions and provide informed consent
  • Ownership and proficiency in using a personal smartphone compatible with the m-Path application (Android or iOS)
  • Willingness to participate for the entire 8-week observation period
Not Eligible

You will not qualify if you...

  • Diagnosis of acquired angioedema or angioedema not related to C1-inhibitor deficiency
  • Severe cognitive or psychiatric disorders preventing independent completion of questionnaires
  • Age under 18 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istituti Clinici Scientifici Maugeri, Milan, Milan 20138

Milan, Italy, 20138

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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