Actively Recruiting
Red Light Treatment in Peripheral Artery Disease
Led by University of Alabama at Birmingham · Updated on 2026-05-01
40
Participants Needed
1
Research Sites
571 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Subjects with a known diagnosis of peripheral artery disease as measured by an abnormal ankle brachial index (\<.9 or \>1.1) will undergo a single 5 min exposure of 670 nm light, 1 cm above the gastrocnemius muscle. Blood flow will be measured by infusion of ultrasound contrast and subsequent acquisition of ultrasound images. 2 blood samples will be collected for measurement of nitric oxide metabolites.
CONDITIONS
Official Title
Red Light Treatment in Peripheral Artery Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged between 18 and 85 years
- Diagnosed with peripheral artery disease defined by ankle brachial index below 0.9 or above 1.1 at rest or during treadmill exercise
- Men and women of all ethnicities eligible
You will not qualify if you...
- Age under 18 years or over 85 years
- Unable to understand the consent process
- Cannot read or speak English
- Active pregnancy
- Hypersensitivity to perflutren contrast agents
- Pulmonary hypertension
- Active illicit drug use
- Untreated blood pressure over 160/95
- Sickle cell disease
- History of intracardiac shunt
- Neurological diseases such as spinal stenosis or unspecified pain disorders
- Any uncontrolled medical conditions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
Research Team
N
Nicole L Lohr, MD,PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here