Actively Recruiting

Phase Not Applicable
Age: 40Years - 85Years
All Genders
NCT05720780

Rehabilitation Training With Music-support & Exercise Tolerance in COPD and CRF Patients.

Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2026-02-23

156

Participants Needed

6

Research Sites

222 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Therapeutic-rehabilitative interventions supported by music can be considered important resources in many clinical contexts. Some studies report the improvement of psychological (i.e. anxiety) and physiological parameters such for example, dyspnea, blood pressure, quality of life, sleep disturbances, etc. through voice, singing, exercise with wind instruments, and sometimes listening to music. Among the various instruments proposed to support the physical training of COPD patients, music was also tested and, in particular, music as a distracting auditory stimulus (DAS) has been used to increase exercise and physical activity adherence and to reduce the perception of dyspnea in COPD subjects. This randomized controlled trial will compare -in patients with COPD and CRF- the effects of the addiction of music to the training on exercise capacity (possible improvement of endurance and reduction of fatigue and dyspnea) with respect to the usual rehabilitation modality (no music).

CONDITIONS

Official Title

Rehabilitation Training With Music-support & Exercise Tolerance in COPD and CRF Patients.

Who Can Participate

Age: 40Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of COPD with FEV1/FVC ratio less than 0.7 after bronchodilator and no functional reversibility
  • Chronic respiratory failure with stable low oxygen levels (PaO2 less than 60 mmHg on room air)
  • Use of long-term oxygen therapy for at least 3 months
  • Clinically stable with pH between 7.38 and 7.42, no recent exacerbations or medication changes in the last 7 days
Not Eligible

You will not qualify if you...

  • Use of home non-invasive ventilation
  • Cognitive impairment with Mini-Mental State Examination score below 22
  • Asthma or evidence of bronchodilator response
  • Pulmonary fibrosis
  • Obstructive sleep apnea syndrome
  • Lung cancer
  • Active infections
  • Neuromuscular, orthopedic, or medical conditions preventing testing
  • Participation in pulmonary rehabilitation within the previous 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Telese

Telese Terme, Benevento, Italy, 82037

Not Yet Recruiting

2

ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Lumezzane

Lumezzane, Brescia, Italy, 25065

Actively Recruiting

3

ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Montescano

Montescano, Pavia, Italy, 27040

Actively Recruiting

4

ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate

Tradate, Varese, Italy, 21049

Actively Recruiting

5

ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Bari

Bari, Italy, 70100

Not Yet Recruiting

6

ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Pavia

Pavia, Italy, 27100

Actively Recruiting

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Research Team

M

Michele Vitacca, MD

CONTACT

T

Tiziana Bachetti, Pharm

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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