Image guided brachytherapy in locally advanced cervical cancer: Improved pelvic control and survival in RetroEMBRACE, a multicenter cohort study.
Alina Sturdza, Richard Pötter, Lars Ulrik Fokdal...
https://pubmed.ncbi.nlm.nih.gov/27134181/Actively Recruiting
Led by Zhejiang Cancer Hospital · Updated on 2022-02-16
300
Participants Needed
1
Research Sites
156 weeks
Total Duration
This research investigates the use of brachytherapy for treating gynecological cancers by looking back at past treatments and outcomes. It aims to evaluate aspects such as the applicator, dose, schedule, technology, imaging methods, 3D printing, effectiveness, and side effects of brachytherapy in this patient group. The study is observational and focuses on female patients with various gynecologic cancers. Participants include females aged 18 to 80 who have previously undergone brachytherapy for gynecological cancers such as cervical, uterine, vulvar, vaginal, or ovarian cancers. The study collects data retrospectively on different types of brachytherapy treatments, including radical, adjuvant, palliative, and others related to gynecologic oncology. The interventions studied involve radiation treatment details and technology used. During the study, researchers review past patient data to measure outcomes like the 5-year overall survival rate, progression-free survival rate, and side effects experienced over five years. There is no active treatment or new intervention instead, the study analyzes historical records to better understand brachytherapys long-term results and safety. The study is sponsored by Zhejiang Cancer Hospital and will continue collecting data until the end of 2027.
CONDITIONS
Retrospective Study of Brachytherapy
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Zhejiang Cancer Hospital
Lead Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 5 years
Participants who have undergone brachytherapy are observed for overall survival, progression-free survival, and side effects over time.
Periodic visits depending on clinical follow-up
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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Alina Sturdza, Richard Pötter, Lars Ulrik Fokdal...
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https://pubmed.ncbi.nlm.nih.gov/23849695/Benjamin D Harris, Sanna Nilsson, Christopher M Poole
https://pubmed.ncbi.nlm.nih.gov/26108891/Zhejiang Cancer Hospital
Lead Sponsor