Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06539767

Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics

Led by Zhujiang Hospital · Updated on 2025-07-28

1000

Participants Needed

2

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemodynamics, ambulatory blood pressure, and imaging histology to study aneurysm instability.

CONDITIONS

Official Title

Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-80 years old, male or infertile female
  • Diagnosed with intracranial aneurysm (IA) by CTA, MRA, or DSA and suitable for endovascular intervention
  • Patient or legal representative understands the research purpose and voluntarily signs informed consent
  • Willing to cooperate with high-resolution magnetic resonance imaging
  • Willing to follow up and complete evaluations according to the clinical research protocol
Not Eligible

You will not qualify if you...

  • Presence of AVM (arteriovenous malformation), Moyamoya disease, or dural arteriovenous fistula (DAVF) related aneurysms
  • Contraindications for high-resolution magnetic resonance imaging
  • Participation in other clinical trials involving drugs or medical devices
  • Severe underlying diseases or extremely poor clinical conditions preventing tolerance of general anesthesia surgery
  • Poor compliance or inability to cooperate with follow-up
  • History of severe allergy to contrast agents
  • Life expectancy less than 2 years
  • Women who are breastfeeding or preparing for pregnancy during the study period

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Zhujiang Hospital

Guangzhou, Guangdong, China

Actively Recruiting

2

Southern medical university, zhujiang hospital

Guangzhou, China

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics | DecenTrialz