Actively Recruiting

Phase 1
Age: 18Years - 75Years
All Genders
NCT07132541

Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)

Led by Minia University · Updated on 2025-09-02

30

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study investigates the safety and efficacy of injecting N-butyl-2-cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the pancreaticojejunostomy (PJ) anastomosis and reduce postoperative pancreatic fistula (POPF) rates.

CONDITIONS

Official Title

Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing pancreaticoduodenectomy for malignant lesions with curative intent based on clinical guidelines
  • Soft pancreatic texture
  • Main pancreatic duct diameter less than 3 mm
  • Informed consent obtained
Not Eligible

You will not qualify if you...

  • Known allergy to cyanoacrylate or Lipiodol
  • Extremely hard or fibrotic pancreas
  • Significant pancreatitis in the pancreatic remnant
  • Active infection at the surgical site
  • Uncontrolled bleeding disorders
  • Severe medical illness making surgery unsafe
  • Inoperable cancer with distant metastases or involvement of other organs
  • Tumors not removable by diagnostic laparoscopy
  • Need for left, central, total pancreatectomy, or palliative surgery
  • Pregnant or breastfeeding women
  • Serious mental disorders
  • Vascular invasion requiring vascular resection
  • Refusal to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Liver and GIT hospital , Minia University

Minya, Minya Governorate, Egypt, 61519

Actively Recruiting

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Research Team

S

Saleh K Saleh, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate) | DecenTrialz