Actively Recruiting

Age: 18Years - 99Years
All Genders
Healthy Volunteers
NCT06552741

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Led by National Institute on Drug Abuse (NIDA) · Updated on 2026-04-08

10000

Participants Needed

1

Research Sites

1164 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Background: People who will participate in research studies need to undergo proper screening, evaluation, and assessment (SEA). SEA helps keep those who participate in studies safe. It also helps ensure accurate study results. The National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP) wants to screen people with alcohol and/or substance use disorders (ASUD) as well as people without ASUD for ongoing studies at NIDA in Baltimore, MD Objective: To screen people with or without ASUD for ongoing studies at NIDA. The ultimate goals are to learn why some people (1) use drugs; (2) stop using drugs; (3) use drugs but do not get addicted; and (4) never use drugs snd to develop ASUD treatments. Eligibility: People aged 18 years and older. They may (1) currently use nicotine, alcohol, opioids, cocaine, or other drugs; (2) no longer use them; or (3) have never used them. Design: Participants will have 1 screening visit that could last up to 8 hours. The visit may be split over more than 1 day. The duration of the screening may vary for each individual based on which studies they are interested in and screened for. The tests they undergo may vary and may include the following: * Physical exam. * Blood, saliva, and urine tests. * Breath samples that test for alcohol and carbon monoxide. * Test of heart function. * Smell test that measures sense of smell. * Tests of memory, attention, and thinking. * Mental health evaluation. * Mock magnetic resonance imaging (MRI) scan. * Questionnaires about alcohol and other drug use, mental health, medical history, and life in general.

CONDITIONS

Official Title

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Who Can Participate

Age: 18Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 99 years old
  • Current or past alcohol or substance use disorders, or no history of these disorders
  • Ability to read, write, and understand English
  • Willingness to comply with all screening procedures and availability during the screening period
  • Ability to understand and willingness to sign a written informed consent document
Not Eligible

You will not qualify if you...

  • Lack of capacity to consent to research participation as determined by the Evaluation to Sign Consent (ESC)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

National Institute on Drug Abuse

Baltimore, Maryland, United States, 21224

Actively Recruiting

Loading map...

Research Team

S

Shannon M Pfistner

CONTACT

L

Lorenzo Leggio, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here