Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT06361407

Sensory and Cognitive Predictions, and Their Disruptions in Schizophrenia

Led by Centre Psychothérapique de Nancy · Updated on 2026-03-25

68

Participants Needed

2

Research Sites

173 weeks

Total Duration

On this page

Sponsors

C

Centre Psychothérapique de Nancy

Lead Sponsor

I

Institut National de la Santé Et de la Recherche Médicale, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

Disturbances in the sense of self and time could play an important role in the development of psychotic symptoms. Previous work has shown that patients have difficulty preparing to process information on the scale of a second, but are abnormally disturbed by slightly asynchronous information on the millisecond scale. In both cases, the anomalies could explain the patients' unusual experience of time. The hypothesis in neurotypical patients is that small delays or asynchronies asynchronies are treated as irrelevant information and ignored and ignored, whereas in patients suffering from schizophrenia they would disrupt the flow of time. This hypothesis is tested with a new visual illusion.

CONDITIONS

Official Title

Sensory and Cognitive Predictions, and Their Disruptions in Schizophrenia

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female
  • Age between 18 and 60 inclusive
  • Signed the consent form before starting any study procedures (guardian or curator consent if applicable)
  • Is a member or beneficiary of a social security scheme
Not Eligible

You will not qualify if you...

  • Have psychoactive substance use disorders as defined by DSM-V
  • Used benzodiazepines or hallucinogens recently (within 5 half-lives before inclusion) or cannabis in the 2 months before inclusion
  • Have neurological diseases or lasting neurological problems
  • Have attention deficit hyperactivity disorder (ADHD)
  • Have borderline personality disorder
  • Have disabling sensory disorders (visual acuity less than 0.8)
  • Are deprived of liberty or under court protection
  • Are pregnant, giving birth, or breastfeeding
  • Are currently excluded from another clinical study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

CHU Sainte Marguerite, APHM

Marseille, France

Actively Recruiting

2

Centre Hospitalier Drôme Vivarais

Montéléger, France

Actively Recruiting

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Research Team

A

Anne Giersch, MD PhD

CONTACT

N

Naoual MELLOUKI BENDIMRED, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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