Actively Recruiting
Role of Ferritin in the Clinical Presentation and Short-Term Prognosis of Diabetic Ketoacidosis
Led by Sohag University · Updated on 2025-05-14
100
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the relationship between serum ferritin levels and both the clinical features and short-term outcomes of patients with diabetic ketoacidosis (DKA). The study aims to determine whether ferritin levels at the time of DKA presentation relate to the severity of the condition and if they can predict short-term prognosis. This investigation is novel, as previous research has looked at ferritin in other acute conditions but not specifically in DKA patients. This observational study will include adult patients diagnosed with DKA according to established criteria, including those with type 1 and type 2 diabetes. The study will exclude individuals with chronic inflammatory diseases, infections, chronic kidney or liver disease, malignancy, iron disorders, and pregnant women. Participants will receive routine hospital care while researchers monitor ferritin levels and clinical status. Participants will be followed for about one year to assess the link between ferritin levels and DKA severity and prognosis. Data collected will include clinical presentation details and laboratory tests related to DKA and ferritin. The main outcome measured is how ferritin levels correlate with disease severity and short-term outcomes. The research is sponsored by Sohag University and aims to provide insight into ferritin as a potential prognostic tool in DKA management.
CONDITIONS
Brief Title
Serum Ferritin and Prognosis of DKA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Diagnosis of diabetic ketoacidosis based on American Diabetes Association criteria: blood glucose >250 mg/dL, arterial pH <7.3, serum bicarbonate <18 mEq/L
- Diagnosis of type 1 or type 2 diabetes mellitus
- Patients presenting with diabetic ketoacidosis
You will not qualify if you...
- Patients younger than 18 years old
- Iron deficiency anemia or iron overload
- Chronic inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, or inflammatory bowel disease
- Acute or chronic infections including bacterial, viral, or fungal infections
- Patients presenting with other acute complications like myocardial infarction or stroke
- Chronic kidney disease patients
- Patients with chronic liver diseases
- Patients with malignancy
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 year
Participants undergo evaluation including serum ferritin measurement and assessment of diabetic ketoacidosis severity.
Periodic visits over the study duration
Duration - Up to 1 year
Participants are observed to determine the correlation between ferritin levels and short-term prognosis of diabetic ketoacidosis.
Follow-up visits as scheduled during the study
Trial Site Locations
Total: 1 location
1
Sohag university Hospitals
Sohag, Sohag Governorate, Egypt, 82524
Actively Recruiting
Research Team
J
Joseph Medhat Sobhy, resident in internal medicine
M
Marium Medhat Sobhy, resident in opthalmology
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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