Actively Recruiting
The South London Stroke Register: Improving the Lives of Stroke Survivors With Data
Led by Guy's and St Thomas' NHS Foundation Trust · Updated on 2024-03-06
2000
Participants Needed
7
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting the South London Stroke Register (SLSR), an ongoing observational study tracking stroke patients in a defined area of South London since 1995. The study aims to understand stroke incidence using the updated WHO ICD-11 definition from April 2022, and to examine long-term outcomes for stroke survivors, including mortality, recurrence, daily living activities, quality of life, and mental health. This research supports stroke survivors and stakeholders by providing detailed data on stroke impacts and care over time. The study includes two participant groups: those registered before April 2022 with strokes defined by ICD-10, followed up at 3 months, 1 year, and then at 5, 10, and 15 years; and those registered after April 2022 with strokes defined by ICD-11, followed up at 3 months and annually up to 5 years. Participants complete interviews or questionnaires covering stroke details, cognitive and mental health, and quality of life. No clinical or radiological procedures are performed as part of the study. Participants are identified through hospital and clinic records across eight hospitals serving the study area. Follow-up interviews occur at specified intervals, lasting about 40 minutes and can be done in person, by phone, or by mail. Researchers collect data on stroke outcomes, recurrence, and use of care services. The study runs through December 2026, with ongoing monitoring of stroke incidence, mortality, and functional status using standardized scales. Participants may withdraw at any time without penalty, and the study keeps data confidential and minimizes participant burden.
CONDITIONS
Brief Title
The South London Stroke Register: Improving the Lives of Stroke Survivors With Data
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed stroke according to WHO ICD-11 clinical definition, including cerebral ischaemic stroke, primary intracerebral haemorrhage, subarachnoid haemorrhage, or stroke not known if ischaemic or haemorrhagic.
- Living in the study area at the time of the first stroke.
- First stroke occurring since January 1, 1995 for enrolled participants or since April 1, 2022 for those under the updated definition.
You will not qualify if you...
- First ever stroke occurred before January 1, 1995.
- Main residence at the time of first stroke was outside the study area.
- Focal neurological signs resolved within 24 hours without CT/MRI evidence of cerebrovascular disease (i.e., transient ischaemic attack).
- CT/MRI scans positive for cerebrovascular disease but no related neurological deficits (asymptomatic cerebrovascular disease).
- Brain lesion causing acute symptoms other than stroke, such as cerebral tumour or metastases.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Participants may be identified through hospital and clinic records or scan reports.
Duration - Initial hospital admission period
Participants undergo routine clinical stroke care including MRI and CT scans to confirm stroke diagnosis.
Notification and data collection occur via hospital visits and medical record reviews.
Duration - Up to 15 years post-stroke depending on cohort
Participants are followed up through interviews to collect information on stroke outcomes, functional status, cognitive function, mental health, and quality of life.
Initial interview followed by interviews at 3 months, 1 year, and then annually up to 5 years for new participants; retrospective cohort includes follow-ups at 5, 10, and 15 years. Interviews may be conducted face-to-face, by telephone, or via postal questionnaire.
Trial Site Locations
Total: 7 locations
1
Barts Health NHS Trust
London, United Kingdom, E1 2ES
Actively Recruiting
2
University College London hospitals NHS Foundation trust
London, United Kingdom, NW1 2PG
Not Yet Recruiting
3
Guy's and St Thomas' NHS Foundation trust
London, United Kingdom, SE1 7EH
Actively Recruiting
4
King's College hospital NHS Foundation Trust
London, United Kingdom, SE5 9RS
Actively Recruiting
5
Chelsea and Westminster Hospital NHS Foundation Trust
London, United Kingdom, Sw10 9NH
Not Yet Recruiting
6
St George's University Hospitals NHS Foundation Trust
London, United Kingdom, SW17 0QT
Actively Recruiting
7
Imperial College Healthcare NHS trust
London, United Kingdom, W2 1BL
Not Yet Recruiting
Research Team
E
Eva S Emmett
M
Matthew O'Connell
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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