Research on Diagnosis and Treatment of Thyroid Nodules and Thyroid Cancer Using Standard Care and Emerging Techniques

What this Trial Is About

This research aims to improve understanding of how thyroid nodules and thyroid cancer are diagnosed and treated. It involves patients diagnosed with or suspected to have these conditions, including those with a family risk of thyroid cancer. The study evaluates both standard medical care and new techniques as they are developed, focusing on diagnosis, therapy, and the natural history of thyroid tumors. Participants will undergo diagnostic imaging, fine needle aspiration biopsies, surgery, and radioiodine scans or therapy as part of their care. The study also assesses the usefulness of blood tests like serum thyroglobulin for detecting tumor recurrence and evaluates individualized radioiodine treatment approaches. Tissue and blood samples will be collected for research using methods such as microscopy and molecular analysis to better understand thyroid function and disease. During the study, participants receive routine clinical care with additional research tests performed. Blood and urine samples will be collected during different thyroid function states for genetic and molecular studies. Researchers will monitor thyroid cancer and thyroid disorders as clinically indicated, using tumor marker tracking and anatomical and functional imaging. The study includes adults and children over 6 months old and involves ongoing evaluation without a fixed end date.

Studies on Tumors of the Thyroid