Actively Recruiting
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
Led by Eli Lilly and Company · Updated on 2026-04-17
222
Participants Needed
27
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study evaluates the efficacy and safety of brenipatide when compared to placebo for reducing the risk of relapse to cigarette smoking in adults who have recently quit. Study participation will last approximately 34 weeks with up to 17 study visits, which includes a 2-week screening period, 24-week treatment period, 8-week safety follow-up period. .
CONDITIONS
Official Title
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have recently quit smoking and are motivated to stay quit from smoking
- Are reliable and willing to make themselves available for the duration of the study and attend required study visits
- Are willing and able to follow study procedures, such as self-injecting the study intervention
You will not qualify if you...
- Have evidence of any substance use disorder within the past 180 days prior to screening, except mild alcohol use disorder, mild cannabis use disorder, or tobacco use disorder
- Have answered "yes" to specific suicidal ideation or behavior questions within the past 6 months
- Have severe chronic obstructive pulmonary disease or any other clinically severe respiratory condition that may pose a risk
- Have participated in a clinical study and received active treatment or have unknown treatment status within 90 days or 5 half-lives before screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 27 locations
1
Woodland Research Northwest
Rogers, Arkansas, United States, 72758
Actively Recruiting
2
Hillcrest Medical Research
DeLand, Florida, United States, 32720
Actively Recruiting
3
TecTum Research
Hollywood, Florida, United States, 33024
Actively Recruiting
4
K2 Medical Research ORLANDO
Maitland, Florida, United States, 32751
Actively Recruiting
5
GTL Medical & Research Group
Miami, Florida, United States, 33173
Actively Recruiting
6
North Georgia Clinical Research
Woodstock, Georgia, United States, 30189
Actively Recruiting
7
Revival Research Institute, LLC
Dearborn, Michigan, United States, 48126
Actively Recruiting
8
Arch Clinical Trials
St Louis, Missouri, United States, 63141
Actively Recruiting
9
Vector Clinical Trials
Las Vegas, Nevada, United States, 89128
Actively Recruiting
10
Rochester Clinical Research, LLC
Rochester, New York, United States, 14609
Actively Recruiting
11
Coastal Carolina Research Center
North Charleston, South Carolina, United States, 29405
Actively Recruiting
12
Circle Clinical Research
Sioux Falls, South Dakota, United States, 57104
Actively Recruiting
13
FutureSearch Trials of Dallas
Dallas, Texas, United States, 75251
Actively Recruiting
14
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77054
Actively Recruiting
15
Health Research of Hampton Roads, Inc.
Newport News, Virginia, United States, 23606
Actively Recruiting
16
Eastside Research Associates
Redmond, Washington, United States, 98052
Actively Recruiting
17
Beijing Chaoyang Hospital, Capital Medical University
Beijing, China, 100020
Actively Recruiting
18
Beijing Anding Hospital - Affiliated Capital University of Medical Science
Beijing, China, 100088
Actively Recruiting
19
Sichuan Provincial People's Hospital
Chengdu, China, 610072
Actively Recruiting
20
2nd Affiliated Hospital Chongqing Medical University
Chongqing, China, 400072
Actively Recruiting
21
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine
Hangzhou, China, 310016
Actively Recruiting
22
Taizhou Hospital of Zhejiang Province
Linhai, China, 317000
Actively Recruiting
23
The first affiliated hospital of Ningbo university
Ningbo, China, 315010
Actively Recruiting
24
The University of Hong Kong-Shenzhen Hospital
Shenzhen, China, 518053
Actively Recruiting
25
Miyazaki RC Clinic
Shinagawa-ku, Japan, 140-0001
Actively Recruiting
26
Samoncho Clinic
Shinjuku, Japan, 160-0017
Actively Recruiting
27
Higashi Shinjuku Clinic
Tokyo, Japan, 169-0072
Actively Recruiting
Research Team
T
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
CONTACT
P
Physicians interested in becoming principal investigators please contact
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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