Actively Recruiting
A Study of Contralateral Limb Block
Led by Mayo Clinic · Updated on 2026-01-06
20
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research is being done to determine if an anesthetic like Lidocaine, may be effective when injected around the sciatic nerve of the intact limb in patients with limb loss pain on the contralateral side.
CONDITIONS
Official Title
A Study of Contralateral Limb Block
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Lower extremity amputation performed more than 12 months before study enrollment
- Phantom or residual limb pain in the amputated limb greater than 4 on the Numeric Rating Scale
- Pain lasting more than 6 months despite at least 2 months of conservative treatments including oral medications, topical medicines, physical therapy, and physical modalities such as heat, cold, electrical nerve stimulation, or phonophoresis
- Willingness to undergo image guided diagnostic nerve block
You will not qualify if you...
- Refusal or inability to participate or provide consent
- Contraindications to diagnostic nerve block
- Pain from non-neurogenic sources
- Current opioid use greater than 50 morphine milligram equivalents per day
- Any interventional pain treatment in the residual limb within the last 30 days
- Severe uncontrolled medical conditions such as hypertensive crisis or decompensated hypothyroidism
- Use of investigational pain drugs within the past 30 days or enrollment in other clinical trials
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Mayo Clinic Health System - Mankato
Mankato, Minnesota, United States, 56001
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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