[Effect of corneal refractive surgery on optical coherence tomography measurements].
A A Shpak, S V Kostenev, I A Mushkova...
https://pubmed.ncbi.nlm.nih.gov/30499539/Actively Recruiting
Led by University of Nebraska · Updated on 2026-03-18
33
Participants Needed
1
Research Sites
N/A
Total Duration
Refractive surgeries such as Lasik are commonly used to correct focusing problems like myopia, or nearsightedness. Patients who undergo these surgeries often need monitoring for other eye conditions such as myopic maculopathy or glaucoma using optical coherence tomography OCT. This research aims to study how refractive surgery might affect OCT measurements in the eye, as changes in the eyes refractive status could influence the test results, but this effect has not been well studied before. The study includes patients aged 19 years or older who are scheduled for refractive surgery. Each patient will have OCT scans performed before the surgery, one day after, and one week after the procedure. The study will analyze changes in macular thickness and other ocular parameters by comparing these measurements over time. Participants will undergo OCT scans at three time points baseline before surgery, 1 day after surgery, and 1 week after surgery. Researchers will measure macular thickness as the primary outcome and also assess secondary outcomes such as choroidal thickness, visual acuity, central corneal thickness, anterior chamber depth, and keratometry. The study will monitor these eye parameters closely to understand any changes following refractive surgery.
CONDITIONS
To Study the Effects of Refractive Surgery on OCT Measurements in the Eye
P
Pukhraj P Rishi, MBBS
T
Tolulope A Fashina, MD
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University of Nebraska
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo refractive surgery and receive immediate post-operative care.
1 visit (in-person)
Duration - 1 week
Participants have follow-up visits to monitor changes in eye parameters after surgery using optical coherence tomography (OCT).
2 visits (1 day and 1 week after surgery, in-person)
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Lead Sponsor