Actively Recruiting

Age: 18Years +
All Genders
NCT07144332

This Study is to Estimate the Efficacy of Hemodialysis Alone for Uric Acid Clearance in Patients on Hemodialysis. In Order to Evaluate the Need of Adjuvant Uric Acid Lowering Therapy

Led by Sohag University · Updated on 2025-08-27

100

Participants Needed

1

Research Sites

29 weeks

Total Duration

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AI-Summary

What this Trial Is About

Background: Uricemia dramatically rises with the stage of chronic kidney disease (CKD) and correlates with its mortality. Hemodialysis (HD) being the most used treatment at the end stage kidney disease in Sohag governorate , we sought to evaluate its efficacy on the clearance of uric acid (UAc) when used alone and twice per week. Methods: A cross-sectional study of all consenting patients with CKD stage 5 recruited at random during hemodialysis sessions at hemodialysis unit in Sohag university hospital from July to December 2025. We collected socio-demographic data, relevant clinical information, hemodialysis related variables, and measured serum uric acid (SUA) levels before and after the dialysis to assess the uric acid clearance. A clearance between 65 and 80% and above 80% was considered as low and good efficacy of hemodialysis respectively

CONDITIONS

Official Title

This Study is to Estimate the Efficacy of Hemodialysis Alone for Uric Acid Clearance in Patients on Hemodialysis. In Order to Evaluate the Need of Adjuvant Uric Acid Lowering Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 or older
  • On maintenance hemodialysis for at least 3 consecutive months
  • Receiving 2 to 3 hemodialysis sessions weekly
  • Consenting to participate in the study
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years old
  • Patients on hemodialysis for less than 3 months
  • Patients currently on uric acid lowering therapy
  • Patients receiving less than 4 hours of hemodialysis per session
  • Patients undergoing emergency dialysis

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Sohag university faculty of medicine

Sohag, Egypt

Actively Recruiting

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Research Team

R

Reham Hussien, master

CONTACT

A

Ali taha, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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This Study is to Estimate the Efficacy of Hemodialysis Alone for Uric Acid Clearance in Patients on Hemodialysis. In Order to Evaluate the Need of Adjuvant Uric Acid Lowering Therapy | DecenTrialz