Actively Recruiting
Study of Infantile Lower Limb Malformations and Deformities
Led by Istituto Ortopedico Rizzoli · Updated on 2025-12-26
1000
Participants Needed
7
Research Sites
234 weeks
Total Duration
On this page
Sponsors
I
Istituto Ortopedico Rizzoli
Lead Sponsor
O
Ospedale Pediatrico Bambino Gesù
Collaborating Sponsor
AI-Summary
What this Trial Is About
The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure. These alterations can be symmetrical or asymmetrical, with potential consequences such as deformities, short stature, and disability. These condictions may impact not only on the physical and the mental function of the children, but also on their family context. Management often requires a multidisciplinary approach for early diagnosis and treatment. Deformities are heterogeneous and necessitate a personalized therapeutic plan. Currently, in pediatric orthopedic surgery there is a lack of an instrument capable of evaluating all these aspects. The advancement of computer-assisted surgery and artificial intelligence could improve treatment customization and involve patients and families in therapeutic decision-making to prevent complications. This study aims to provide support for clinical practice to promote a systematic, comprehensive, and sequential evaluation of lower limb deformities in developmental age, from which epidemiological data and evidence on treatment approaches used in major referral centers can be extrapolated.
CONDITIONS
Official Title
Study of Infantile Lower Limb Malformations and Deformities
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Under 18 years old at the time of initial orthopedic evaluation
- Diagnosed with congenital or acquired musculoskeletal deformity in one or both lower limbs
- Provided informed consent to participate in the study
You will not qualify if you...
- Patient or parent/legal guardian refuses to participate in the study
- Mild limb differences without functional limitations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy, 40136
Actively Recruiting
2
Istituto Giannina Gaslini
Genova, Italy
Not Yet Recruiting
3
Galeazzi Orthopedic Institute
Milan, Italy
Not Yet Recruiting
4
Policlinico San Matteo
Pavia, Italy
Not Yet Recruiting
5
Istituto Nazionale Tumori Regina Elena
Roma, Italy
Not Yet Recruiting
6
Ospedale Pediatrico Bambino Gesù
Roma, Italy
Not Yet Recruiting
7
Istituto Clinico Humanitas
Rozzano, Italy
Not Yet Recruiting
Research Team
G
Giovanni Trisolino, MD
CONTACT
A
Alessandro Depaoli, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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