Actively Recruiting

Age: 0 - 18Years
All Genders
NCT06519175

Study of Infantile Lower Limb Malformations and Deformities

Led by Istituto Ortopedico Rizzoli · Updated on 2025-12-26

1000

Participants Needed

7

Research Sites

234 weeks

Total Duration

On this page

Sponsors

I

Istituto Ortopedico Rizzoli

Lead Sponsor

O

Ospedale Pediatrico Bambino Gesù

Collaborating Sponsor

AI-Summary

What this Trial Is About

The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure. These alterations can be symmetrical or asymmetrical, with potential consequences such as deformities, short stature, and disability. These condictions may impact not only on the physical and the mental function of the children, but also on their family context. Management often requires a multidisciplinary approach for early diagnosis and treatment. Deformities are heterogeneous and necessitate a personalized therapeutic plan. Currently, in pediatric orthopedic surgery there is a lack of an instrument capable of evaluating all these aspects. The advancement of computer-assisted surgery and artificial intelligence could improve treatment customization and involve patients and families in therapeutic decision-making to prevent complications. This study aims to provide support for clinical practice to promote a systematic, comprehensive, and sequential evaluation of lower limb deformities in developmental age, from which epidemiological data and evidence on treatment approaches used in major referral centers can be extrapolated.

CONDITIONS

Official Title

Study of Infantile Lower Limb Malformations and Deformities

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Under 18 years old at the time of initial orthopedic evaluation
  • Diagnosed with congenital or acquired musculoskeletal deformity in one or both lower limbs
  • Provided informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Patient or parent/legal guardian refuses to participate in the study
  • Mild limb differences without functional limitations

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy, 40136

Actively Recruiting

2

Istituto Giannina Gaslini

Genova, Italy

Not Yet Recruiting

3

Galeazzi Orthopedic Institute

Milan, Italy

Not Yet Recruiting

4

Policlinico San Matteo

Pavia, Italy

Not Yet Recruiting

5

Istituto Nazionale Tumori Regina Elena

Roma, Italy

Not Yet Recruiting

6

Ospedale Pediatrico Bambino Gesù

Roma, Italy

Not Yet Recruiting

7

Istituto Clinico Humanitas

Rozzano, Italy

Not Yet Recruiting

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Research Team

G

Giovanni Trisolino, MD

CONTACT

A

Alessandro Depaoli, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Study of Infantile Lower Limb Malformations and Deformities | DecenTrialz