Actively Recruiting

Age: 50Years - 85Years
All Genders
NCT06534658

Study on Multimodal Imaging and Molecular Imaging Techniques in Degenerative Dementia

Led by Ruijin Hospital · Updated on 2024-08-02

1000

Participants Needed

8

Research Sites

474 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project is a multicenter observational study that establishes a longitudinal cohort of patients with Alzheimer's disease and other dementias based on neuroimaging, molecular imaging, biological and digital markers to explore new solutions such as dementia disease mechanism, diagnosis, condition evaluation, and prognosis assessment.

CONDITIONS

Official Title

Study on Multimodal Imaging and Molecular Imaging Techniques in Degenerative Dementia

Who Can Participate

Age: 50Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 60 and 6485 years old, male or female
  • Meet the diagnostic criteria for dementia or mild cognitive impairment (MCI)
  • Neuropsychological score: MMSE between 15 and 28 points
  • Clinical Dementia Rating (CDR) 64 1 point
  • Patients and their families provide informed consent
Not Eligible

You will not qualify if you...

  • Presence of other neurological diseases that may cause brain dysfunction (such as depression, brain tumors, Parkinson's disease, metabolic encephalopathy, encephalitis, multiple sclerosis, epilepsy, brain trauma, normal intracranial pressure hydrocephalus)
  • Presence of systemic diseases that may cause cognitive impairment (such as liver dysfunction, renal dysfunction, thyroid dysfunction, severe anemia, folic acid or vitamin B12 deficiency, syphilis, HIV infection, alcohol or drug abuse)
  • Conditions preventing cooperation with cognitive examinations
  • Contraindications to MRI scanning
  • Mental and neurological retardation
  • Refusal to provide blood samples
  • Refusal to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 8 locations

1

Chinese People's Liberation Army General Hospital

Beijing, Beijing Municipality, China

Actively Recruiting

2

First Affiliated Hospital of Zhejiang University School of Medicine

Hanzhong, Hangzhou, China

Actively Recruiting

3

Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

Cangzhou, Hebei, China

Actively Recruiting

4

The Second Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

Actively Recruiting

5

Qilu Hospital of Shandong University, Qingdao Branch

Qingdao, Shandong, China

Actively Recruiting

6

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China, 200025

Actively Recruiting

7

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China, 200025

Actively Recruiting

8

The First Affiliated Hospital of China Medical University

Shenyang, Shenyang, China

Actively Recruiting

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Research Team

J

Jintao Wang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Study on Multimodal Imaging and Molecular Imaging Techniques in Degenerative Dementia | DecenTrialz